Evidence map›Paper›PMID 40542877›Full record

ArticleAbdominal radiology (New York)2026

Direct comparison of full protocol MRI and modified non-contrast MRI in staging of cervical cancer: a retrospective study.

Fahimeh Zeinalkhani, Peyman Kamali Hakim, Maryam Aghasi, Fatemeh Mahdavi Sabet, Reihaneh Mortazavi Ardestani, Yasamin Baghban, Mahrooz Malek, Hadise Zeinalkhani, Sina Delazar, Fatemeh Shakki Katouli and 3 more

Abstract readComparative Study
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In one paragraph

Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

13 authors.

Fahimeh ZeinalkhaniAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Peyman Kamali HakimAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Maryam AghasiDepartment of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Fatemeh Mahdavi SabetIslamic Azad University, Tehran, Islamic Republic of Iran.
Reihaneh Mortazavi ArdestaniAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Yasamin BaghbanAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Mahrooz MalekAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Hadise ZeinalkhaniShahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Sina DelazarAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Fatemeh Shakki KatouliAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Fahimeh AzizinikAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Sanaz MoghaddamimonaghiDepartment of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Saeed MohammadzadehAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran. saeed.mohamadzadeh2001@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCervical cancer is the fourth most common cancer and the fourth leading cause of cancer death among women worldwide. Appropriate treatment can reduce mortality rate and improve prognosis, where the choice of appropriate treatment option is closely related to the preoperative staging. In this study, we compared full protocol MRI (including contrast-enhanced images) and modified protocol (including only T2-weighted sequence and DWI + ADC map images) in preoperative cervical cancer staging based on the 2018 Federation of Gynecology and Obstetrics (FIGO) classification system. MATERIAL AND

methodsIn this retrospective cross-sectional study, pelvic MRIs of 128 patients with cervical cancer were evaluated. For all patients, staging was performed by two independent radiologists according to the 2018 FIGO Staging Classification, first based on modified protocol and then based on full protocol MRI. Inter-modality agreement was evaluated by Cohen's kappa, intraclass correlation coefficient (ICC), and concordance correlation coefficient (CCC).

resultsThere was very good agreement between the modified and full protocols in preoperative staging of cervical cancer (weighted kappa: 0.967) with a low number of discrepancies. There was also a high level of agreement between two modalities in the determination of parametrium, pelvic side wall, bladder, intestine, uterine, and lymph node involvements, as well as hydronephrosis and vascular encasement. Tumors at stage I had significantly higher ADC values compared to higher-stage tumors (p-value: 0.003).

conclusionBased on our study, modified MRI (including T2WI and DWI images) had substantial agreement with full protocol MRI in preoperative cervical cancer staging, suggesting its potential as a reliable contrast-free alternative for clinical practice.

Indexed as

Magnetic Resonance ImagingUterine Cervical NeoplasmsAdultAgedAged, 80 and overContrast MediaCross-Sectional StudiesFemaleHumansMiddle AgedNeoplasm StagingRetrospective StudiesContrast MediaCervical cancerContrast-enhanced MRIDiffusion-weighted imagingPreoperative staging

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.