Evidence map›Paper›PMID 40542872›Full record

Trial reportArchives of orthopaedic and trauma surgery2025

Comparison of periarticular injection and low-concentration high-volume suprainguinal fascia Iliaca plane block in total knee arthroplasty: a randomized prospective study.

Mehmet Cenk Turgut, Elif Oral Ahiskalioglu, Yunus Emre Karapinar, Ela Medetoglu Koksal, Cagatay Engin, Erkan Cem Celik, Muhammed Enes Aydin, Ahmet Murat Yayik

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehmet Cenk TurgutAtatürk University, Erzurum, Turkey.
Elif Oral AhiskaliogluAtatürk University, Erzurum, Turkey.
Yunus Emre KarapinarAtatürk University, Erzurum, Turkey.
Ela Medetoglu KoksalAtatürk University, Erzurum, Turkey.
Cagatay EnginAtatürk University, Erzurum, Turkey.
Erkan Cem CelikAtatürk University, Erzurum, Turkey.
Muhammed Enes AydinAtatürk University, Erzurum, Turkey. enesmd@msn.com.
Ahmet Murat YayikAtatürk University, Erzurum, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe suprainguinal fascia iliaca plane block (SFIPB) has been used effectively for postoperative analgesia in hip surgeries due to its extensive dermatomal coverage. This technique may also serve as an alternative in knee surgeries. However, studies investigating the use of SFIPB in total knee arthroplasty (TKA) are limited. This study evaluates the efficacy of SFIPB compared to periarticular infiltration (PAI) in TKA, focusing on postoperative opioid consumption, pain scores, motor function, and rehabilitation outcomes.

methodsThis randomized controlled trial included 70 patients undergoing TKA, allocated to either the SFIPB group or the PAI group. Postoperative pain management was standardized across groups using patient-controlled fentanyl analgesia. Primary outcomes included opioid consumption over 48 h, and secondary outcomes assessed pain scores, quadriceps strength, mobilization times, range of motion (ROM), and rehabilitation test results.

resultsSFIPB resulted in significantly reduced opioid consumption at 24 and 48 h compared to PAI (p < 0.001). Pain scores assessed via visual analogue scale (VAS) were lower in the SFIPB group, particularly for anterior knee pain during rest and movement (p < 0.05). SFIPB also demonstrated superior rehabilitation outcomes, with improved quadriceps strength (p = 0.002) and better performance on the Time Up and Go (TUG) test. Both groups reported minimal side effects, but opioid-related nausea and vomiting were less frequent in the SFIPB group.

conclusionThe use of SFIPB with a dilute, high-volume local anesthetic was superior to PAI by reducing opioid consumption and opioid-related side effects without impairing motor function or patient mobilization. This highlights its potential as an effective analgesic technique in TKA.

Indexed as

Anesthetics, LocalArthroplasty, Replacement, KneeNerve BlockPostoperative PainAgedAnalgesia, Patient-ControlledAnalgesics, OpioidFemaleHumansInjections, Intra-ArticularMaleMiddle AgedPain MeasurementProspective StudiesRange of Motion, ArticularAnalgesics, OpioidAnesthetics, LocalPeriarticular infiltrationSuprainguinal fascia Iliaca plane blockTotal knee arthroplasty

Identifiers

PMID40542872
PMCPMC12182502

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.