ReviewEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025
Spike-shaped ossification of the posterior longitudinal ligament combined with dural ossification: a case report and literature review on imaging diagnosis and pathogenesis.
Review in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOssification of the posterior longitudinal ligament (OPLL) combined with dural ossification (DO) significantly increases the technical difficulty and risk of complications in spinal canal decompression surgery. The pathological mechanisms underlying DO remain incompletely elucidated, and standardized imaging diagnostic criteria are currently lacking. CASE PRESENTATION: This study reports a 59-year-old female diagnosed with mixed-type cervical spondylopathy, OPLL at C5/6 and C6/7 levels, and hypertension. Preoperative computed tomography (CT) revealed flat-type OPLL at C5/6 and spike-shaped OPLL protruding into the spinal canal at C6/7. Intraoperative exploration identified regional plate-like hardening of the dura mater at C6/7. Following anterior cervical discectomy combined with ossified dura mater floating, the patient exhibited significant neurological improvement without postoperative complication. CONLUSION: CT demonstrates diagnostic value for mature-stage DO but lacks sensitivity in early ossification phases. Spike-shaped OPLL may promote dural ossification by inducing mechanical stress-mediated transfer of osteogenic factors. Future research may need to explore artificial intelligence-based novel imaging biomarkers to enhance early diagnostic accuracy for DO.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.