Evidence map›Paper›PMID 40542786›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2025

Protective Role of Bee Venom (Apis mellifera) Against Kidney Damage in Female Mice with Cancer.

Mohanad Salam Hussein, Shahad Falah Abass, Ahmed Flayyih Hasan, Ali G Al-Dulimi, Hany M El-Wahsh

Abstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mohanad Salam HusseinNational Center of Hematology, Mustansiriyah University, Baghdad, Iraq.
Shahad Falah AbassCollege of Pharmacy, Mustansiriyah University, Baghdad, Iraq.
Ahmed Flayyih HasanBiotechnology Research Center, Al-Nahrain University, Baghdad, Iraq.
Ali G Al-DulimiCollege of Dentistry, University of Bilad Alrafidain, Diyala, 32001, Iraq.
Hany M El-WahshDepartment of Marine Biology, Faculty of Marine Sciences, King Abdulaziz University, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is a dreadful disease that has a huge, negative impact on people's personal, social, and financial lives, as well as their healthcare. The purpose of our study is to evaluate the capability of Apis mellifera (A.M.), to reduce the renal toxicity and tissue damage caused by the Ehrlich ascites carcinoma (EAC) in mice.

methodsA total of forty female Swiss albino mice were divided evenly among four groups (G1, control; G2, A.M.; G3, EAC; and G4, EAC+ A.M.).

resultsThe current results revealed that EAC caused renal tissue damage, and increase in the serum urea, creatinine, potassium, and chloride ion levels. They also caused a significant decrease in the levels of sodium and calcium ions in the blood, as compared to the normal control. Furthermore, EAC caused a variety of pathological alterations in the glomeruli and renal tubules, including mild glomerular shrinkage, notable cellular infiltration, marked renal injury, and marked renal tissue degradation. When EAC was treated with A.M. (EAC+ A.M.), the kidney structure and function improved, in comparison to the use of EAC alone. The serum urea, creatinine, potassium, and chloride ion levels decreased, but the sodium and calcium ion levels increased.

conclusionIt was possible to conclude that A.M. could shield the kidneys from renal toxicity caused by the EAC cells.

Indexed as

Bee VenomsCarcinoma, Ehrlich TumorKidneyKidney DiseasesProtective AgentsAnimalsBeesCreatinineFemaleMiceUreaBee VenomsCreatinineProtective AgentsUreaEACKidney functionsMicevenom (Apis mellifera)

Identifiers

PMID40542786
PMCPMC12374532

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.