SynthesisJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2025
Cyanoacrylate Adhesive Versus Sutures for Free Gingival Graft Fixation: A Systematic Review and Meta-Analysis of Clinical Outcomes.
Synthesis in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cyanoacrylate Adhesive Versus Sutures for Free Gingival Graft Fixation: A Systematic Review and Meta-Analysis of Clinical Outcomes.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Pooled it
- Molecular Design of Underwater Adhesive Copolymers: Synergy Between Long-Chain Alkyl Crystallization-Melting Switching and Carboxyl Group Interfacial Interactions.Materials (Basel, Switzerland) · 2026Article
- Effect of Suturing and Adhesive Fixation on Free Gingival Graft Stability: An Ex-Vivo Porcine-Model Study.Clinical and experimental dental research · 2026Article
- Digitally Guided Frontal Sinus Fracture Fixation: A Point-of-Care "In-House" Biomodel Protocol with Cyanoacrylate-Assisted Fragment Stabilization.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare clinical outcomes of cyanoacrylate adhesive (GLU) and sutures (SUT) for the fixation of free gingival grafts (FGG) around natural teeth. MATERIALS AND
methodsA systematic search of MEDLINE, Embase, Cochrane Library, Scopus, and Google Scholar was conducted up to March 2025. Randomized controlled trials (RCTs) comparing GLU and SUT as fixation methods for FGG were included in a meta-analysis. Potential moderators, including publication year, follow-up duration, sample size, baseline clinical parameters, and study-level covariates, were investigated.
resultsTen RCTs were included. No significant differences were observed between GLU and SUT for recession reduction (mean difference [MD] = 0.49 mm; 95% CI: -0.53 to 1.50; p = 0.08), keratinized tissue (KT) height gain (MD = 0.01 mm; 95% CI: -1.58 to 1.59; p = 0.99), or graft shrinkage (MD = 0.26; 95% CI: -0.13 to 0.66; p = 0.15). A statistically significant but clinically negligible difference favored GLU for probing depth reduction (MD = 0.063 mm; 95% CI: 0.007 to 0.118; p = 0.044). Meta-regression identified smoking, tissue thickness, graft dimension, and follow-up duration as moderators of treatment outcomes.
conclusionNo significant differences were observed between GLU and SUT in clinical outcomes following FGG procedures around natural teeth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.