ReviewMycoses2025
Zoonotic and Anthropophilic Trichophyton mentagrophytes Complex Infection in Human: An Update and Narrative Review.
Review in Mycoses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Review
- Empowering fungal infection research with single-cell RNA sequencing.Communications biology · 2026Review
- Development and validation of a risk nomogram model for predicting superficial fungal infections in patients with type 2 diabetes mellitus : a cross-sectional study.BMC infectious diseases · 2026Article
- Application of a One-Health Approach for Dermatophyte Infections.Tropical medicine and infectious disease · 2026Article
- Global Emergence ofInfection and drug resistance · 2026Review
- Emerging Zoonotic Dermatophytosis: A 10-Year Case Series from a Dermatology Clinic in Japan.Mycopathologia · 2025Article
- Superficial Fungal Infections in Children-What Do We Know?Journal of clinical medicine · 2025Review
- Dual-Emission FRET-PCR Outperforms SYBR Green and EvaGreen for Accurate Discrimination of Primary Canine Dermatophytes:Journal of fungi (Basel, Switzerland) · 2025Article
- Zoonotic and Anthropophilic Trichophyton mentagrophytes Complex Infection in Human: An Update and Narrative Review.Mycoses · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrichophyton mentagrophytes species complex comprises dermatophytes responsible for common superficial fungal infections affecting keratinised tissues. Recent shifts in taxonomy and increasing antifungal resistance-necessitate an updated understanding of this fungal complex.
objectiveThis narrative review provides a comprehensive update on the taxonomy, host immune response and clinical genotyping of the T. mentagrophytes complex, with a focus on zoonotic and anthropophilic infections in humans.
methodsA comprehensive literature search was conducted across PubMed and Scopus using MeSH terms and relevant keywords related to T. mentagrophytes, T. interdigitale, and T. indotineae. Eligible English-language publications up to March 2025-including original research, case reports, reviews and guidelines-were included.
resultsThe T. mentagrophytes complex includes several genotypes with distinct transmission profiles. Genotypes III/III* are primarily zoonotic; genotype VII is sexually transmitted, especially in MSM populations; genotype VIII (T. indotineae) is anthropophilic and associated with terbinafine resistance. Infection involves keratinocyte adhesion, enzymatic skin barrier degradation and activation of pro-inflammatory cytokines and antimicrobial peptides. Both innate and adaptive immunity, particularly Th1 and Th17 responses, are critical for fungal clearance, whereas chronic infections are associated with impaired T-cell function and skewed Th2 responses.
conclusionEmerging genotypes and drug resistance within the T. mentagrophytes complex pose increasing clinical challenges. Awareness of transmission patterns, immune evasion mechanisms and resistance profiles is essential for accurate diagnosis and effective management of dermatophytosis.
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