Evidence map›Paper›PMID 40542518›Full record

SynthesisAutism research : official journal of the International Society for Autism Research2025

The Association Between Maternal Asthma and Child Autism: A Systematic Review and Meta-Analysis.

Renee van der Schaaf, Vanessa E Murphy, Soriah Harvey, Paige Dent, Alison Lane, Olivia Whalen

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Autism research : official journal of the International Society for Autism Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. The Association Between Maternal Asthma and Child Autism: A Systematic Review and Meta-Analysis.Autism research : official journal of the International Society for Autism Research · 2025
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Renee van der SchaafSchool of Psychological Sciences, University of Newcastle, Newcastle, New South Wales, Australia.ORCID 0000-0001-6010-3587
Vanessa E MurphySchool of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.ORCID 0000-0003-3282-1324
Soriah HarveySchool of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.
Paige DentSchool of Psychological Sciences, University of Newcastle, Newcastle, New South Wales, Australia.
Alison LaneOlga Tennison Autism Research Centre, La Trobe University, Melbourne, Victoria, Australia.
Olivia WhalenSchool of Psychological Sciences, University of Newcastle, Newcastle, New South Wales, Australia.ORCID 0000-0001-8927-6959

Funding

Asthma Australia G2300013Australian Government Research Training Program ScholarshipMedical Research Future Fund APP1196252
6 · The paper itself

Abstract

Maternal asthma has been linked to child autism. In this study, we systematically reviewed observational studies published between July 2001 and February 2024 that assessed maternal asthma during pregnancy (exposure) and child autism (outcome). Databases searched included MEDLINE, CINAHL, EMBASE, and PsycINFO. Of the 350 potential studies, 19 met the inclusion criteria (2,530,716 participants; 73,065 autistic participants). Quality was assessed with the Newcastle-Ottawa Scale. Meta-analyses using proportions and odds ratios were conducted using the Mantel-Haenszel method with a random-effects model. Compared to women without asthma, there was an increased odds of child autism with any history of maternal asthma (OR = 1.32; 95% CI = 1.21, 1.44; I

Indexed as

AsthmaAutistic DisorderPregnancy ComplicationsPrenatal Exposure Delayed EffectsChildFemaleHumansMothersPregnancyasthmaasthma medicationautismchildinfantmaternalpregnancy

Identifiers

PMID40542518
PMCPMC12384736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.