ArticleThe New phytologist2025
Towards the control of biofilm formation in Anabaena (Nostoc) sp. PCC7120: novel insights into the genes involved and their regulation.
Article in The New phytologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Transcriptional and cellular reprogramming inCurrent research in microbial sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Cyanobacteria are major components of biofilms in light-exposed environments, contributing to nutrient cycling, nitrogen fixation and global biogeochemical processes. Although nitrogen-fixing cyanobacteria have been successfully used in biofertilization, the regulatory mechanisms underlying biofilm formation remain poorly understood. In this work, we have identified 183 novel genes in Anabaena sp. PCC7120 potentially associated with exopolysaccharide (EPS) biosynthesis and biofilm formation, unveiling conserved and novel regulatory connections shared with phylogenetically distant bacteria. Anabaena possesses homologues of two-component systems such as XssRS and ColRS from Xanthomonas spp., and AnCrpAB from Methylobacillus, suggesting that these homologues play essential or advantageous roles in biofilm formation across diverse bacterial lineages. Additionally, Anabaena features homologues of several proteins exhibiting the GG-secretion motif typical of small proteins required for biofilm formation in unicellular cyanobacteria. A wide array of biofilm-related genes in Anabaena, including major gene clusters participating in the synthesis and translocation of EPS and key regulatory proteins involved in the control of biofilms in other bacteria are modulated by ferric uptake regulator proteins. These findings link the control of biofilm formation in Anabaena to environmental cues such as metal availability, desiccation and nitrogen levels, providing new insights to improve the use of nitrogen-fixing cyanobacterial biofilms in sustainable agriculture and environmental management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.