Evidence map›Paper›PMID 40542449›Full record

ArticleAntimicrobial resistance and infection control2025

Effect of catheter dwell time on the risk of central line-associated bloodstream infections in central venous catheters and peripherally inserted central catheters.

Vassiliki Pitiriga, Elsa Campos, John Bakalis, Konstantinos Sagris, George Georgiadis, George Saroglou, Athanasios Tsakris

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Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

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7citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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  6. Combination effect of meropenem and antifungals againstJournal of medical microbiology · 2025
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Vassiliki PitirigaDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, Athens, 11527, Greece.
Elsa CamposDepartment of Internal Medicine, Metropolitan Hospital, 9 Ethnarchou Makariou Street, Piraeus, Neo Faliro, 18547, Greece.
John BakalisDepartment of Internal Medicine, Metropolitan Hospital, 9 Ethnarchou Makariou Street, Piraeus, Neo Faliro, 18547, Greece.
Konstantinos SagrisDepartment of Internal Medicine, Metropolitan Hospital, 9 Ethnarchou Makariou Street, Piraeus, Neo Faliro, 18547, Greece.
George GeorgiadisDepartment of Internal Medicine, Metropolitan Hospital, 9 Ethnarchou Makariou Street, Piraeus, Neo Faliro, 18547, Greece.
George SaroglouDepartment of Internal Medicine, Metropolitan Hospital, 9 Ethnarchou Makariou Street, Piraeus, Neo Faliro, 18547, Greece.
Athanasios TsakrisDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, Athens, 11527, Greece. atsakris@med.uoa.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding the impact of catheter dwell time on the risk of central-line associated bloodstream infections (CLABSIs) is crucial to developing effective infection prevention strategies. The aim of the study was to evaluate the relationship between catheter dwell time and the risk of CLABSIs caused by multidrug-resistant and common pathogens in patients with central venous catheters (CVCs) and peripherally inserted central catheters (PICCs).

methodsWe retrospectively analysed data from patients admitted consecutively to a tertiary care Greek hospital from 2018-2020. Events were categorized into three groups based on 10-days' intervals: group 1 (≤ 10 days), group 2 (11-20 days), and group 3 (> 21 days).

resultsΑ total of 84 patients (mean age 56.4 ± 19.6 years) were included in the study. Among them, 62 (73.8%) had CVC, while 22 (26.2%) had PICC placement. In the CVC cohort, a statistically significant difference in CLABSI rates was observed, with rates of 4.49, 5.57, and 8.54 per 1,000 catheter/days for groups 1, 2, and 3 respectively (p < 0.001). Similarly, higher rates of MDROs were found in group 3, with rates of 2.93, 3.71, and 4.47 per 1,000 catheter/days for groups 1, 2, and 3, respectively (p = 0.01). Regarding the PICC cohort, significant differences in CLABSI rates were observed among the three groups, with rates of 0.93, 2.25, and 1.67 per 1,000 catheter/days for groups 1, 2, and 3, respectively (p < 0.001).

conclusionOur results emphasize the critical role of catheter selection and duration management in mitigating CLABSI risk, especially for patients with CVCs.

Indexed as

BacteremiaCatheterization, Central VenousCatheterization, PeripheralCatheter-Related InfectionsCentral Venous CathetersAdultAgedFemaleGreeceHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTime FactorsBloodstream infectionCatheterizationCentral line-associated bloodstream infectionCentral venous catheterDwell timePeripherally inserted central catheter

Identifiers

PMID40542449
PMCPMC12181930

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.