ArticleParasites & vectors2025
Experimental BTV-3 and BTV-8 infection of Culicoides sonorensis biting midges.
Article in Parasites & vectors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- The changing landscape of bluetongue in northern Europe.Journal of medical entomology · 2026Review
- Bluetongue in the Mediterranean Basin: An Overview of Recent Hotspots and Advances in Vaccine Technologies.Microorganisms · 2026Review
- Cattle Abortions and Congenital Malformations Due to Bluetongue Virus Serotype 3 in Southern Belgium, 2024.Viruses · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundBluetongue virus (BTV) is the etiologic agent of a major infectious disease of livestock and is transmitted between its ruminant hosts by Culicoides biting midges. The first outbreak ever recorded in central Europe was caused by serotype BTV-8 and led to a major epidemic. In 2023, serotype BTV-3 emerged in the Netherlands and spread rapidly to neighbouring countries. Compared with the BTV-8 outbreak in 2006, the course of the BTV-3 epizootic is more severe, in regards to clinical signs and faster spread of the virus.
methodsTo explore possible causes of the different epidemiologies, we performed laboratory infection experiments and compared the replication properties of BTV-8 and BTV-3 in Culicoides sonorensis biting midges.
resultsOral infection with BTV-3 resulted in a significantly higher viral load in the infected midges with demonstrated replication than BTV-8 infection.
conclusionsThe higher viral load observed in midges with BTV-3 replication than in midges with BTV-8 replication may be a factor contributing to the observed faster outbreak progression of the current BTV-3 outbreak in comparison to the BTV-8 outbreak in 2006/2007.
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