ArticleInternational journal of retina and vitreous2025
Assessment of tilt and decentration of a 4-point scleral fixated intraocular lens using an innovative digital measurement methodology.
Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Improvement of uncorrected visual acuity and contrast sensitivity using Aurovue Vivid Continuous Focus Vision (CFV) lens in cataract patients at RSCM Kirana.BMC ophthalmology · 2026Article
- Needle bevel-guided standardisation of scleral tunnel formation in intrascleral haptic fixation: a quantitative geometric analysis.BMC ophthalmology · 2026Article
- Outcomes of intraocular lens exchange with combined pars plana vitrectomy and retropupillary iris-claw lens fixation.International journal of retina and vitreous · 2026Article
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9 authors.
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Abstract
backgroundThe study underscores the importance of conducting objective measurements of intraocular lens (IOL) tilt and decentration over time to provide evidence of IOL stability. The goals were to validate a new method for measuring tilt and decentration of secondary implants and evaluate the postoperative functional and anatomic outcomes of 4-support IOL scleral fixation.
methodsThis prospective study (7 patients, seven eyes) was conducted from October 2020 to April 2021 at the Department of Ophthalmology, Federal University of São Paulo, São Paulo, and Technological Institute of Aeronautics, São José dos Campos, Brazil. The patients underwent combined vitrectomy and implantation of a 4-point scleral fixation IOL. The subjective refraction with the logarithm of the minimum angle of resolution (logMAR) best-corrected visual acuity (BCVA), slit-lamp examination, Goldmann applanation tonometry, wide-field retinography, and Scheimpflug corneal tomography and topography were performed preoperatively and postoperatively. Macular optical coherence tomography (OCT) was performed to assess the presence of macular edema. Anterior-segment OCT and ultrasound biomicroscopy (UBM) were performed to measure IOL positioning. The method for measuring IOL positioning was validated. Surgery outcomes included BCVA, refraction, and IOL tilt and decentration.
resultsHigh intra-class correlations (0.781 to 0.999) were found for the intra- and inter-observer measurements of the UBM and OCT images. Measurements obtained using the scleral spur (SS) as an anatomic reference are comparable to those obtained using the iris pigmented epithelium (IPE) plane as a reference. Conversely, the measurements taken with OCT images cannot be compared to those obtained with UBM images. The logMAR BCVA improved from 0.59 ± 0.13 preoperatively to 0.24 ± 0.34 at 6 months postoperatively (P = 0.001). The mean tilt using anterior-segment OCT was 1.15 ± 1.26 degrees. The mean decentration on UBM images was 0.58 ± 0.63 mm; no significant changes in IOL position were observed between 1 and 6 months postoperatively.
conclusionThe methodology exhibits strong reproducibility and enabled valid comparisons of tilt and decentration across the SS and IPE. Four-support IOL scleral fixation yields favorable surgical outcomes with physiologic IOL position and maintains stability throughout the follow-up period.
trial registrationThe Federal University of São Paulo institution’s Research Ethics Committee reviewed and approved this study protocol (Approval Number, 4.261.258).
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