Evidence map›Paper›PMID 40542399›Full record

ArticleTrials2025

Digital education and exercise therapy versus minimal intervention for young people at high risk of early onset knee osteoarthritis after ACL reconstruction: a study protocol for the Stop OsteoARthritis (SOAR) randomized controlled trial.

Jackie L Whittaker, Amanda Cammalleri, Candice Archibald, Alexandra Brooks-Hill, Patrick Chin, Sarah Clark, Jennifer C Davis, Alison M Hoens, Michael A Hunt, Karin Kausky and 15 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06195423 (The Stop Osteoarthritis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06195423 narecruitingnot on this map

The Stop Osteoarthritis (SOAR) Hybrid Effectiveness-Implementation Type 1 Randomized Controlled Trial for Young People At-High-Risk of Early Onset Knee Osteoarthritis

TypeinterventionalSponsorUniversity of British ColumbiaRan2024 to 2028Enrolled210ConditionsKnee Injuries, Anterior Cruciate Ligament Rupture, Osteoarthritis, KneeArmsStop OsteoARthritis (SOAR) program, Living Well after ACLR program
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Jackie L WhittakerDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada. jackie.whittaker@ubc.ca.ORCID http://orcid.org/0000-0002-6591-4976
Amanda CammalleriDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Candice ArchibaldKootenay Therapy Center, Cranbrook, Canada.
Alexandra Brooks-HillDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Patrick ChinDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Sarah ClarkDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Jennifer C DavisCentre for Aging SMART, University of British Columbia, Vancouver, Canada.
Alison M HoensDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Michael A HuntDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Karin KauskyWhistler 360, Whistler, Canada.
Angelina KoDo Well Therapy, Vancouver, Canada.
Lise LeveilleDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Linda C LiDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Parth LodhiaDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Justin M LoscialeInformatice, Decision-Enhancement and Analytic Science Centre of Innovation, George E. Whalen Veteran Affairs Medical Centre, Salt Lake City, USA.
Maxi MiciakFaculty of Rehabilitation Medicine, University of Alberta, Edmonton, Canada.
Amber D MosewichFaculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Canada.
Adnan SheikhDepartment of Radiology, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Trish Silvester-LeeArthritis Research Canada, Vancouver, Canada.
Linda K TruongDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Dominic WadeNexus Rehabilitation, Coquitlam, Canada.
David R WilsonCentre for Aging SMART, University of British Columbia, Vancouver, Canada.
Hui XieArthritis Research Canada, Vancouver, Canada.
Xian He YanDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Ewa M RoosDepartment of Musculoskeletal Function and Physiotherapy, University of Southern Denmark, Odense, Denmark.

Funding

Arthritis Society 23-0259Institute of Gender and Health FEM19229Institute of Gender and Health FEM196028Institute of Musculoskeletal Health and Arthritis PTJ527549
6 · The paper itself

Abstract

backgroundPeople who tear their anterior cruciate ligament and have reconstruction surgery (ACLR) are at elevated risk of inactivity, obesity, and early-onset knee osteoarthritis. Consensus recommendations to prevent post-traumatic knee osteoarthritis include person-centered education and exercise-based treatments. The effectiveness of these recommendations is unknown. This study will assess if a digital education and exercise therapy intervention is superior to minimal intervention for improving knee-related symptoms, function, and quality of life in young people after ACLR.

methodsThe Stop OsteoARthritis (SOAR) study is a parallel, two-arm, assessor-blinded, superiority, hybrid effectiveness-implementation type 1 randomized controlled trial. After baseline testing, 166 participants aged 16-35 years, 9-36 months past, a first-time ACLR with ongoing symptoms will be randomly allocated to one of two treatment groups (1:1 ratio, stratified by sex). Ongoing symptoms will be defined as not meeting a Patient Acceptable Symptom State (PASS) on the averaged Knee injury and Osteoarthritis Outcome Score pain, symptoms function in sport and recreation, and quality-of-life subscales (KOOS DISCUSSION: By assessing the effect, implementation, and efficiency of a digital education and exercise-based intervention designed to improve the knee health of young people at increased risk of knee osteoarthritis, this study will provide a basis for future scale-up to help curb the mounting burden of osteoarthritis.

trial registrationClinicalTrials.gov NCT06195423. Registered on December 22, 2023.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionExercise TherapyKnee JointOsteoarthritis, KneePatient Education as TopicAdolescentAdultEquivalence Trials as TopicFemaleHumansMaleQuality of LifeRandomized Controlled Trials as TopicRecovery of FunctionRisk FactorsAction planningEducationExercise therapyGoal-settingPhysical therapyPost-traumatic osteoarthritisPreventionSelf-managementTelerehabilitation

Identifiers

PMID40542399
PMCPMC12181937

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.