Evidence map›Paper›PMID 40542382›Full record

ArticleThe journal of headache and pain2025

Migraine through puberty and menopausal transition-data from the population-based Norwegian Women and Health study (NOWAC).

Nora Stensland Bugge, Kjersti Grøtta Vetvik, Karl Bjørnar Alstadhaug, Tonje Braaten

Abstract read
In one paragraph

Article in The journal of headache and pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Neurology of Menopause.Current neurology and neuroscience reports · 2026
    Review
  3. Article
  4. Migraine and the menopause transition.Menopause (New York, N.Y.) · 2026
    Article
  5. Article
  6. Observational
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nora Stensland BuggeDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway. nora.stensland-bugge@uit.no.
Kjersti Grøtta VetvikDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Karl Bjørnar AlstadhaugDepartment of Neurology, Nordland Hospital, Bodø, Norway.
Tonje BraatenDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMigraine considerably affects women during their reproductive years. This cross-sectional study uses data from the Norwegian Women and Health study (NOWAC) and investigates the typical age at migraine onset and cessation in women and assesses how reproductive milestones affect migraine patterns.

methods4825 women with a history of migraine were included in the study. Participants completed a questionnaire that procured detailed information on their migraine characteristics and reproductive histories.

resultsAverage ages at migraine onset and cessation were 27.8 and 49.7 years, respectively. Migraine onset after age 50 was reported in 9.2% of the participants. Although 80.7% reported cessation before age 60, 46.3% continued to experience migraines postmenopause. Women with migraine with aura were more likely to report migraine onset before menarche than those with migraine without aura.

conclusionMigraines usually resolve during the fifth decade of a woman's life and menstruation cessation does not necessarily equate to migraine cessation, as almost half of the women continued to experience migraines postmenopause, and one in five after 60 years. Migraine symptom persistence in a significant proportion of postmenopausal women underscores the need for continued management and research on the factors influencing migraine prevalence in later life stages.

Indexed as

MenopauseMigraine DisordersPubertyAdultAge of OnsetCross-Sectional StudiesFemaleHumansMiddle AgedNorwaySurveys and QuestionnairesYoung AdultMenarcheMenopauseMigraineNorwegian Women and Health studyPostmenopausal women

Identifiers

PMID40542382
PMCPMC12180204

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.