Evidence map›Paper›PMID 40542365›Full record

ReviewWorld journal of surgical oncology2025

Ruptured phyllodes tumors of the breast: a comprehensive case series and literature review on clinical challenges.

Chularat Duangkaew, Areewan Somwangprasert, Kirati Watcharachan, Phanchaporn Wongmaneerung, Chagkrit Ditsatham

Abstract readCase ReportsReview
In one paragraph

Review in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chularat DuangkaewDivision of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Amphoe Muang, Chiang Mai, 50200, Thailand.
Areewan SomwangprasertDivision of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Amphoe Muang, Chiang Mai, 50200, Thailand.
Kirati WatcharachanDivision of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Amphoe Muang, Chiang Mai, 50200, Thailand.
Phanchaporn WongmaneerungDivision of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Amphoe Muang, Chiang Mai, 50200, Thailand.
Chagkrit DitsathamDivision of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Amphoe Muang, Chiang Mai, 50200, Thailand. chagkrit.d@cmu.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phyllodes tumors are rare fibroepithelial breast neoplasms, predominantly affecting women aged 35 to 55. While most phyllodes tumors are manageable, those exceeding 10 cm, termed giant phyllodes tumors, can lead to rare complications such as breast rupture due to rapid growth and pressure necrosis. This study presents three cases of ruptured phyllodes tumors treated at Chiang Mai University Hospital, along with a review of previously reported cases, highlighting the associated clinical challenges and treatment strategies. Surgical intervention, typically through wide local excision, is the standard treatment. However, in ruptured cases, which often present as extensive masses involving the entire breast, surgical management is more complex and may necessitate a mastectomy. Given the limited number of reported cases and our own findings, the benefit of adjuvant radiotherapy following mastectomy remains unclear. The low recurrence rate among patients who did not receive radiotherapy raises questions about its necessity.

Indexed as

Breast NeoplasmsPhyllodes TumorFemaleHumansMastectomyPrognosisRadiotherapy, AdjuvantRupture, SpontaneousGiant phyllodes tumorMalignant phyllodes tumorPhyllodes tumorRuptured phyllodes tumor

Identifiers

PMID40542365
PMCPMC12180164

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.