Evidence map›Paper›PMID 40542247›Full record

ArticlePlant cell reports2025

Characterization of PAMP-induced peptides and mechanistic insights into SlPIP2-mediated defense in tomato.

Ruirui Yang, Hongbo Wei, Jiaxuan Zhu, Zhiyuan Xue, Siya Zeng, Jun Meng, Yushi Luan

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Article in Plant cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ruirui YangMOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, 116024, China.
Hongbo WeiMOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, 116024, China.
Jiaxuan ZhuMOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, 116024, China.
Zhiyuan XueMOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, 116024, China.
Siya ZengMOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, 116024, China.
Jun MengSchool of Computer Science and Technology, Dalian University of Technology, Dalian, 116024, China.
Yushi LuanMOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, 116024, China. ysluan@dlut.edu.cn.ORCID http://orcid.org/0000-0001-9397-9171

Funding

National Natural Science Foundation of China 32230091National Natural Science Foundation of China 32472738
6 · The paper itself

Abstract

key messageSlPIP2 modulates the expression of PR genes, the activity of antioxidant enzymes, and the accumulation of defense-related metabolites in tomato, and concurrently contributes to enhanced resistance against Phytophthora infestans and Botrytis cinerea. Tomato (Solanum lycopersicum), as one of the most popular horticultural crops, is widely cultivated worldwide, however, its yield and quality is continually threatened by P. infestans. Plant peptides are engaged in the regulation of plant growth and immunity. PAMP-induced Peptides (PIPs) are new class of signaling peptides with diverse biologic roles in the regulation of plant defense responses. In this study, a total of seven SlPIP genes were identified in the tomato genome, and their expression profiles were analyzed under P. infestans infection. Among the SlPIP family members, SlPIP2 exhibited a significant response to pathogen infection. Through a combination of virus-induced gene silencing (VIGS) and gene overexpression, we demonstrated that SlPIP2 precursor (SlprePIP2) positively regulates tomato resistance. Notably, exogenous application of SlPIP2 enhanced plant defense responses, increasing resistance not only to P. infestans but also to B. cinerea, thereby highlighting its potential role in conferring broad-spectrum disease defense. To elucidate how SlPIP2 affected to tomato resistance, we performed transcriptomic analysis on tomato seedlings sprayed with H

Indexed as

PeptidesPlant DiseasesPlant ProteinsSolanum lycopersicumBotrytisDisease ResistanceGene Expression Regulation, PlantPhytophthora infestansPlants, Genetically ModifiedPeptidesPlant ProteinsDisease resistancePathogensPlant peptideTomatoTranscriptome

Identifiers

PMID40542247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.