Evidence map›Paper›PMID 40542223›Full record

Observational studyJournal of human hypertension2025

Hypertensive urgencies and emergencies in the cardiology emergency department: epidemiology, patient profile, and management.

Panagiotis Theofilis, Nikolaos Nakas, Thomais Lamprou, Kalliopi Touchantzidou, Aikaterini Vordoni, Vasilios Thimis, Despina Smirloglou, Athanasios Kotsakis, Rigas G Kalaitzidis

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of human hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. In Hypertensive Urgency With Volume Overload-Intravenous Loop Diuretic may be Indicated.Journal of clinical hypertension (Greenwich, Conn.) · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Panagiotis TheofilisCenter for Nephrology "G. Papadakis", General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Ioannina, Greece.ORCID http://orcid.org/0000-0001-9260-6306
Nikolaos Nakas2nd Cardiology Department, General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Nikaia, Greece.
Thomais Lamprou2nd Cardiology Department, General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Nikaia, Greece.
Kalliopi Touchantzidou2nd Cardiology Department, General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Nikaia, Greece.
Aikaterini VordoniCenter for Nephrology "G. Papadakis", General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Ioannina, Greece.
Vasilios ThimisCenter for Nephrology "G. Papadakis", General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Ioannina, Greece.
Despina SmirloglouCenter for Nephrology "G. Papadakis", General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Ioannina, Greece.
Athanasios Kotsakis2nd Cardiology Department, General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Nikaia, Greece.
Rigas G KalaitzidisCenter for Nephrology "G. Papadakis", General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Ioannina, Greece. rigaska@gmail.com.ORCID http://orcid.org/0000-0002-7773-7575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertensive urgencies (HU) and hypertensive emergencies (HE) are common conditions in the cardiology emergency department (ED), often requiring urgent intervention. Despite their clinical significance, data on patient characteristics, etiologies, and management strategies remain limited. This study aimed to assess the epidemiology, clinical profile, and management of HU and HE in a tertiary cardiology ED. A single-center, observational study was conducted over 12 months, enrolling patients diagnosed with HU/HE (BP ≥ 180/120 mmHg). Demographic data, medical history, symptoms, etiologic factors, and antihypertensive treatments were recorded. Serial blood pressure (BP) measurements were taken to assess BP reduction during the ED stay. Of 4010 cardiology ED visits, 83 patients (2.1%) had HU/HE (median age 65 years, 45.8% male). Most had a history of hypertension (73.5%), with frequent coexisting smoking (56.6%) and dyslipidemia (43.4%). Common symptoms included dyspnea (19.3%) and chest pain (25.3%). Stress (26.8%) and increased salt intake (15.9%) were common etiologic factors. HE was diagnosed in 18 cases (21.7%), and 12.7% of HU cases required hospitalization. Mean BP on admission was 200/100 mmHg, with SBP and DBP reductions of 41 mmHg (-21%) and 18 mmHg (-17%), respectively. Nitrates, anxiolytics, and combination therapies resulted in the greatest BP reductions. In conclusion, HU and HE are frequently observed in hypertensive patients with additional cardiovascular risk factors. Target-organ damage is not solely related to BP levels, emphasizing the need for individualized management strategies.

Indexed as

Antihypertensive AgentsBlood PressureCardiology Service, HospitalEmergency Service, HospitalHypertensionAgedAged, 80 and overEmergenciesFemaleHumansHypertensive CrisisMaleMiddle AgedRisk FactorsAntihypertensive Agents

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.