Evidence map›Paper›PMID 40542186›Full record

ArticleNature chemistry2025

Accessing sulfonamides via formal SO

Myojeong Kim, Carys E Obertone, Christopher B Kelly, Christopher A Reiher, Cristina Grosanu, James C Robertson, Mark D Levin

Abstract read
PubMed Publisher
In one paragraph

Article in Nature chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Direct Deaminative Alkynylation of Aliphatic Primary Amines.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Anomeric Amides: Valuable Reagents in Synthetic Organic Chemistry.Angewandte Chemie (International ed. in English) · 2026
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Myojeong KimDepartment of Chemistry, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-3852-3566
Carys E ObertoneDepartment of Chemistry, University of Chicago, Chicago, IL, USA.ORCID 0009-0009-8904-1450
Christopher B KellyDiscovery Process Research, Johnson & Johnson Innovative Medicine, Spring House, PA, USA. ckelly5@its.jnj.com.ORCID 0000-0002-5530-8606
Christopher A ReiherParallel Medicinal Chemistry, Johnson & Johnson Innovative Medicine, Spring House, PA, USA. creiher@its.jnj.com.ORCID 0000-0002-6171-3480
Cristina GrosanuHigh-Throughput Purification, Johnson & Johnson Innovative Medicine, Spring House, PA, USA.
James C RobertsonIn Silico Discovery, Johnson & Johnson Innovative Medicine, Spring House, PA, USA.
Mark D LevinDepartment of Chemistry, University of Chicago, Chicago, IL, USA. marklevin@uchicago.edu.ORCID 0000-0002-4461-363X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional group interconversions are particularly sought after by medicinal chemists as a means to enable both lead optimization and library diversification. Here we report SO

Indexed as

CarbonNitrogenSulfonamidesSulfur DioxideAminesMolecular StructureAminesCarbonNitrogenSulfonamidesSulfur Dioxide

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.