Evidence map›Paper›PMID 40542175›Full record

ArticleScientific reports2025

Seasonal variation effect on different Physalis peruviana L. (Solanaceae) waste extracts and investigation of their efficacy against Culex pipiens and Musca domestica.

Esraa A Elhawary, Mohamed M Baz, Reham M Mostafa, Abdelfattah M Selim, Mohammed H Alruhaili, Hattan S Gattan, Mohammed E Gad

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Phytochemical Characterization ofFood science & nutrition · 2026
    Article
  4. Article
  5. Article
  6. Sustainable MnOPharmaceuticals (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esraa A ElhawaryDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, 11566, Egypt. esraa.elhawary@pharma.asu.edu.eg.
Mohamed M BazEntomology Department, Faculty of Science, Benha University, Benha, Qalyubiya, 13518, Egypt.
Reham M MostafaBotany and Microbiology Department, Faculty of Science, Benha University, Benha, Qalyubiya, 13518, Egypt.
Abdelfattah M SelimDepartment of Animal Medicine (Infectious Diseases), College of Veterinary Medicine, Benha University, Toukh, 13736, Egypt. abdelfattahselim54@gmail.com.
Mohammed H AlruhailiDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, 21589, Jeddah, Saudi Arabia.
Hattan S GattanDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, 22254, Jeddah, Saudi Arabia.
Mohammed E GadDepartment of Zoology and Entomology, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disease-carrying insects transmit many of the most serious human diseases. After decades of repeated use of insecticides, all of these vector species have demonstrated the ability to develop resistance to insecticides. This has necessitated the development of more efficient and environmentally safe alternatives in the form of biopesticides. Plants contain a wide range of potential phytochemicals that target a specific target, are rapidly biodegradable, environmentally friendly, and have a variety of therapeutic effects, making them a treasure trove of biological materials. Moreover, this has led to the creation of highly effective new drugs. The present study aims to demonstrate the specific active components in Physalis peruviana calyces that were collected in two consecutive fruiting seasons through UPLC/MS and multivariate data analyses. The extracts were prepared using 70% methanol/water and petroleum ether for each season, then evaluated against disease-carrying vectors, Culex pipiens and Musca domestica. The UPLC/MS analysis resulted in the tentative identification of fifty-four secondary metabolites belonging mainly to flavonoids, phenolic acids, withanolides, triterpenoids, phenyl propanoids, and many others. After various intervals of exposure, plant extracts in this study showed high insecticidal activity against mosquito and housefly larvae, Cx. pipiens, and M. domestica. Data showed that P. peruviana methanol extract (POM) appeared to be most effective (MO%) against Cx. pipiens (LC

Indexed as

CulexHousefliesInsecticidesPhysalisPlant ExtractsAnimalsLarvaSeasonsInsecticidesPlant ExtractsBioinsecticideCulexMuscaPeruvianaPhysalisSolanaceaeWaste

Identifiers

PMID40542175
PMCPMC12181326

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.