Evidence map›Paper›PMID 40542151›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Reliability of [

Kasper Foged Guldbrandsen, Markus Nowak Lonsdale, Hanne Marie Nellemann, Catharina Mølgaard Bylov, Joan Fledelius, Karin Hjorthaug, Barbara Jolanta Jørgensen, Martin Krakauer, Mette Schødt, Peter Michael Gørtz and 12 more

Abstract readMulticenter Study
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Kasper Foged GuldbrandsenDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark. kasper.guldbrandsen@gmail.com.ORCID 0000-0002-1921-0150
Markus Nowak LonsdaleDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Hanne Marie NellemannDepartment of Radiology, Aarhus University Hospital, Aarhus, Denmark.
Catharina Mølgaard BylovDepartment of Radiology, Aarhus University Hospital, Aarhus, Denmark.
Joan FledeliusDepartment of Nuclear Medicine & PET-Centre, Aarhus University Hospital, Aarhus, Denmark.
Karin HjorthaugDepartment of Nuclear Medicine & PET-Centre, Aarhus University Hospital, Aarhus, Denmark.
Barbara Jolanta JørgensenDepartment of Radiology, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Martin KrakauerDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Mette SchødtDepartment of Radiology, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark.
Peter Michael GørtzDepartment of Nuclear Medicine, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark.
Mie Kiszka NielsenDepartment of Radiology, Odense University Hospital, Odense, Denmark.
Anne Lerberg NielsenDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Annemarie Gjelstrup AmtoftDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Elisabeth Albrecht-BesteDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Danijela DejanovicDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Marie Josée Zareh Lausten-ThomsenDepartment of Radiology, University Hospital of Southern Denmark, Lillebaelt Hospital - Vejle, Vejle, Denmark.
Paw Christian HoldgaardDepartment of Nuclear Medicine, University Hospital of Southern Denmark, Lillebaelt Hospital - Vejle, Vejle, Denmark.
Magdalene KubikDepartment of Nuclear Medicine, Aalborg University Hospital, Aalborg, Denmark.
Søren Steen NielsenDepartment of Nuclear Medicine, Aalborg University Hospital, Aalborg, Denmark.
Oke GerkeDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Torben Riis RasmussenDepartment of Respiratory Medicine and Allergy, Aarhus University Hospital, Aarhus, Denmark.
Barbara Malene FischerDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ([

methodsNine teams from seven centers, each team consisting of a nuclear medicine specialist and a radiologist, participated in the study. A total of 150 PET/CT scans were selected, and each was independently reviewed by two randomly assigned teams. Scans were performed six months post-treatment for scheduled recurrence assessment in stage Ia-IIIc NSCLC patients. Each scan was evaluated for suspicion of recurrence using two methods; without any pre-specified criteria (conventional assessment) and using pre-specified, qualitative criteria (Hopkins criteria). Both scoring methods were compared to a reference standard to assess accuracy.

resultsConventional assessment showed moderate interobserver agreement (κ = 0.55, 95% CI 0.41-0.69; 79% overall agreement) for the diagnosis of recurrence. Hopkins criteria demonstrated substantial agreement (κ = 0.61, 95% CI 0.45-0.77; 87% overall agreement). There was no difference in the area under the curve (AUC) between conventional assessment (0.80, 95% CI 0.72-0.88) and Hopkins criteria (0.82, 95% CI 0.74-0.90) compared to the reference standard (p = 0.21).

conclusionsInterobserver agreement for [

Indexed as

Carcinoma, Non-Small-Cell LungFluorodeoxyglucose F18Lung NeoplasmsPositron Emission Tomography Computed TomographyAgedAged, 80 and overFemaleHumansMaleMiddle AgedObserver VariationRadiopharmaceuticalsReproducibility of ResultsFluorodeoxyglucose F18Radiopharmaceuticals[18F]FDG PET/CTInterobserver agreementLung cancerRecurrenceSurveillance

Identifiers

PMID40542151
PMCPMC12660443

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.