ArticleScientific reports2025
Comparative lesion metrics analysis of very high power and high power short duration radiofrequency ablation in a Porcine ex vivo model.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ablation for Atrial Fibrillation: Can We Individualise Therapy or Should One Size Fit All?Reviews in cardiovascular medicine · 2025Review
- First-in-Human Application of Very High-Power Short-Duration RF Ablation for Refractory AVNRT: A Case Report.Life (Basel, Switzerland) · 2025Article
- Catheter Ablation of Premature Ventricular Contractions from Right Ventricular Outflow Tract: Concept and Application of Very-High-Power, Very-Short-Duration as a First-Line Ablation Strategy.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-power, short-duration (HP-SD) ablation is a well-established radiofrequency (RF) ablation protocol in cardiac electrophysiology. Recently, very high-power, short-duration (vHP-SD) ablation has emerged as an alternative. This study compares lesion metrics between vHP-SD and HP-SD ablation protocols using the latest irrigated RF catheter with temperature-based power regulation, considering the impact of contact force (CF). RF ablations were performed in a porcine ex vivo model using myocardial preparations in a circulating saline bath. Three protocols were applied: vHP-SD (90 W for 4s), HP-SD-4 (50 W for 4s) and HP-SD-15 (50 W for 15s). A total of 360 lesions in 12 hearts were analyzed (vHP-SD: 120; HP-SD-4: 120, HP-SD-15: 120). The HP-SD-4 protocol produced the lowest mean lesion depth (2.42 ± 0.61 mm vs. 3.16 ± 0.41 mm vs. 4.49 ± 0.66 mm, p < 0.001), mean maximum lesion diameter (6.02 ± 1.00 mm vs. 7.34 ± 0.92 mm vs. 9.13 ± 1.59 mm), and mean lesion volume (52.0 ± 22.5 mm³ vs. 96.4 ± 28.8 mm³ vs. 211.4 ± 95.3 mm³, p < 0.001), followed by the vHP-SD protocol. In contrast, the HP-SD-15 protocol resulted in the highest values across all three parameters. Lesion depth, maximum lesion diameter, and lesion volume increased significantly with higher contact force (p < 0.001, p = 0.002, and p = 0.003, respectively). However, the absolute changes in these lesion dimensions were relatively small compared to those observed with power-controlled RF catheters, likely due to the effect of temperature-based power regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.