Evidence map›Paper›PMID 40542082›Full record

Observational studyScientific reports2025

Electrophysiological findings for peripheral nerves of lower limb in women with stress urinary incontinence and non-specific low back pain.

Doaa A Abdel Hady, Lama Eid, Mina George, Osama M Abdel Raheem

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Doaa A Abdel HadyDepartment of Physical Therapy for Women's Health, Faculty of Physical Therapy, Deraya University, El Minya, Egypt. doaaabdlnaser@gmail.com.
Lama EidFaculty of Physical Therapy, Deraya University, El Minya, Egypt.
Mina GeorgeFaculty of Physical Therapy, Deraya University, El Minya, Egypt.
Osama M Abdel RaheemDepartment of Physical Therapy for Neurology, Faculty of Physical Therapy, Deraya University, El Minya, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress urinary incontinence (SUI) and nonspecific low back pain (NSLBP) are prevalent conditions that significantly affect women's quality of life. Recent studies have identified a connection between these conditions and dysfunction in the peripheral nerves of the lower limb. This study aims to compile existing knowledge on the electrophysiological findings in the peripheral nerves of the lower limb in women experiencing SUI and NSLBP. This was a prospective observational study involving fifty healthy women and women suffering from SUI and NSLBP. The participants were aged between 25 and 35 and had a body mass index (BMI) ranging from 20 to 24. The primary outcome measures focused on evaluating lower-limb peripheral nerves in women with SUI and NSLBP. There was an increase in both distal and proximal latencies of the tibial nerve, along with a significant decrease in distal and proximal amplitudes and nerve conduction velocity (NCV) in group A when compared to group B (p < 0.001). For the peroneal nerve, group A showed a significantly higher distal latency and a significantly lower NCV (p < 0.001), while no significant differences were observed in proximal latency or the proximal and distal amplitudes between the two groups (p > 0.05). Regarding the sural nerve, group A had significantly higher onset latency and lower amplitude and NCV compared to group B (p < 0.01). These findings reveal statistically significant nerve conduction abnormalities in tibial, peroneal, and sural nerve conduction in women suffering from stress urinary incontinence (SUI) and non-specific low back pain. The tibial nerve displayed extended distal and proximal latencies, diminished amplitudes, and lower nerve conduction velocity (NCV). The peroneal nerve showed prolonged distal latency and a reduced NCV, while the sural nerve had an extended onset latency, decreased amplitude, and slower NCV. The tibial nerve showed the most changes, including extended latencies and lower conduction velocity, implying both axonal and demyelinating involvement. These changes, supported by large effect sizes, high thresholds commonly associated with clinically meaningful decline, and may have functional consequences.

Indexed as

Low Back PainLower ExtremityPeripheral NervesUrinary Incontinence, StressAdultElectrophysiological PhenomenaFemaleHumansNeural ConductionPeroneal NerveProspective StudiesTibial NerveElectrophysiological findingNon-specific low back painPeroneal nerveStress urinary incontinence (SUI)Sural nerveTibial nerve

Identifiers

PMID40542082
PMCPMC12181281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.