Evidence map›Paper›PMID 40541953›Full record

ReviewTranslational psychiatry2025

The value of multimodal neuroimaging in the diagnosis and treatment of post-traumatic stress disorder: a narrative review.

Hanyi Zhang, Yining Hu, Yiying Yu, Zheng Zhou, Yueru Sun, Chang Qi, Lihua Yang, Hua Xie, Junran Zhang, Hongru Zhu

Abstract readReview
In one paragraph

Review in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hanyi ZhangMental Health Center, West China Hospital, Sichuan University, Chengdu, China.
Yining HuWest China School of Public Health, Sichuan University, Chengdu, China.
Yiying YuWest China School of Public Health, Sichuan University, Chengdu, China.
Zheng ZhouWest China School of Public Health, Sichuan University, Chengdu, China.
Yueru SunWest China School of Public Health, Sichuan University, Chengdu, China.
Chang QiWest China School of Public Health, Sichuan University, Chengdu, China.
Lihua YangWest China School of Public Health, Sichuan University, Chengdu, China.
Hua XieChildren's National Hospital and Center for Neuroscience, Washington, DC, USA.ORCID http://orcid.org/0000-0003-3462-0147
Junran ZhangMed-X Center for Informatics, Sichuan University, Chengdu, Sichuan, China.
Hongru ZhuMental Health Center, West China Hospital, Sichuan University, Chengdu, China. zhuhongru@wchscu.edu.cn.ORCID http://orcid.org/0000-0001-8420-581X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82171513
6 · The paper itself

Abstract

Post-traumatic stress disorder (PTSD) is a delayed-onset or prolonged persistent psychiatric disorder caused by individuals experiencing an unusually threatening or catastrophic stressful event or situation. Due to its long duration and recurrent nature, unimodal neuroimaging tools such as computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and electroencephalography (EEG) have been widely used in the diagnosis and treatment of PTSD for early intervention. However, as compared with an unimodal approach, a multimodal imaging approach can better capture integrated neural mechanisms underlying the occurrence and development of PTSD, including predisposing factors, changes in neural activity, and physiological mechanisms of symptoms. Moreover, a multimodal neuroimaging approach can aid the diagnosis and treatment of PTSD, facilitate searching for biomarkers at different stages of PTSD, and explore biomarkers for symptomatic improvement. However, at present, the majority of PTSD studies remain unimodal, while the combination of multimodal brain imaging data with machine learning will become an important direction for future research.

Indexed as

BrainMultimodal ImagingNeuroimagingStress Disorders, Post-TraumaticElectroencephalographyHumansMagnetic Resonance ImagingPositron-Emission Tomography

Identifiers

PMID40541953
PMCPMC12181266

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.