Evidence map›Paper›PMID 40541829›Full record

ArticleJournal of affective disorders2025

Benchmarking empirical severity for the Yale-Brown Obsessive Compulsive Scale-Second Edition.

Caitlin M Pinciotti, Juliana Avery, Chencheng Zhang, Josselyn S Muñoz, Dayan Berrones, Vanessa Zavala Cruz, Andrew D Wiese, Jacey L Anderberg, Renee M Frederick, Tomás Miño and 9 more

Abstract read
In one paragraph

Article in Journal of affective disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Caitlin M PinciottiPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
Juliana AveryPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
Chencheng ZhangShanghai Jiao Tong University School of Medicine, Shanghai, China.
Josselyn S MuñozPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
Dayan BerronesPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
Vanessa Zavala CruzPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
Andrew D WiesePsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
Jacey L AnderbergPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States; Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, United States.
Renee M FrederickPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States; Department of Psychology, University of Houston, Houston, TX, United States.
Tomás MiñoCentro Interdisciplinario de Neurociencia de Valparaíso, Valparaíso, Chile.
Nuria LanzagortaInvestigación Clínica, Grupo Médico Carracci, Ciudad de México, Mexico.
Juan Camilo RestrepoFacultad de Psicología y Ciencias del Comportamiento, Universidad de La Sabana, Chía, Cundinamarca, Colombia.
Marcos E Ochoa-PanaifoUniversidad Privada del Norte, Lima, Peru.
Latin American Trans-ancestry INitiative for OCD genomics (LATINO)
Brazilian Obsessive-Compulsive Spectrum Work Group (GTTOC)
Wayne K GoodmanPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
James J CrowleyDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Eric A StorchPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States. Electronic address: eric.storch@bcm.edu.
Matti CervinPsychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States; Department of Clinical Sciences, Lund University, Lund, Sweden.

Funding

Utilizing Community-Based Participatory Action Research Approaches to Inform Equitable OCD Genetics Research in Diverse PopulationsU01MH125062 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI STORCH, ERIC A. · 2021 to 2025
$2.6M
Administrative Supplement: 1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorderU01MH125050 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CROWLEY, JAMES JOSEPH, PATO, MICHELE T · 2021 to 2025
$1.8M
Genomics of OCD in Latin American CommunitiesR00MH128540 · NIMH · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Carolina Cappi · 2025 to 2026
$498k
NIMH NIH HHS R00 MH128540NIMH NIH HHS U01 MH125050NIMH NIH HHS U01 MH125062
6 · The paper itself

Abstract

The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is considered the primary instrument for assessing the presence and severity of obsessive-compulsive disorder (OCD). Conceptual and empirical critiques inspired the development of an updated version of the instrument, the Yale-Brown Obsessive Compulsive Scale-Second Edition (Y-BOCS-II), with a higher ceiling of OCD severity to better differentiate between severe and the most debilitating OCD presentations, among other revisions. The Y-BOCS-II has demonstrated sound psychometric properties across diverse samples. Empirically derived severity benchmarks have been proposed for the original Y-BOCS, yielding somewhat different ranges than what has been commonly used in clinical and research settings, yet severity benchmarks for the Y-BOCS-II have yet to be established. Using a diverse, pooled sample of 2982 children and adults with OCD or obsessive-compulsive and related concerns across 13 countries, receiver-operating characteristic (ROC) analyses yielded severity benchmarks that largely mirrored the original Y-BOCS at the lower range of scores and extended the previously established benchmarks at the higher range of scores, owing to the increased ceiling of the instrument. The optimal benchmark ranges were determined as: non-/sub-clinical (0-14), mild (15-21), moderate (22-34), severe (35-50). Similar benchmarks were present across sex and age groups, and their accuracy was adequate in both a holdout sample and an independent sample of OCD patients from China (n = 78). Limitations and implications for the use of the Y-BOCS-II in clinical and research settings are discussed.

Indexed as

BenchmarkingObsessive-Compulsive DisorderPsychiatric Status Rating ScalesAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedPsychometricsReproducibility of ResultsROC CurveSeverity of Illness IndexYoung AdultAssessmentObsessive-compulsive disorderReceiver-operating characteristic analysesSeverity benchmarksYale-Brown Obsessive Compulsive Scale-Second Edition

Identifiers

PMID40541829
PMCPMC13112087

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.