Evidence map›Paper›PMID 40541527›Full record

ArticleeNeuro2025

Evidence That Dmrta2 Acts through Repression of

Xueyi Shen, Jithu Anirudhan, Ambrin Fatima, Estelle Plant, Tünde Szemes, Zélie Bouveret, Marc Keruzore, Sadia Kricha, Xinsheng Nan, Alba Sabaté San José and 17 more

Abstract read
In one paragraph

Article in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Xueyi ShenLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Jithu AnirudhanLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Ambrin FatimaDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.
Estelle PlantService of Molecular Virology, Department of Molecular Biology and ULB-Cancer Research Centre, Université Libre de Bruxelles, Gosselies 6041, Belgium.ORCID https://orcid.org/0000-0001-8584-1068
Tünde SzemesLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Zélie BouveretINSERM U1052, CNRS UMR5286, Université Claude Bernard Lyon1, Centre de Recherche en Cancérologie de Lyon, Lyon F-69000, France.ORCID https://orcid.org/0009-0000-6643-8775
Marc KeruzoreLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Sadia KrichaLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Xinsheng NanNeuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, United Kingdom.
Alba Sabaté San JoséLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Samuel BianchinLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Bérénice VeraghenLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Louis-Paul DelhayeLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium.
Bilal Ahmad MianDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.
Lubaba Bintee KhalidDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.
Farhan AliDepartment of Paediatrics and Child Health, Aga Khan University, Karachi 74800, Pakistan.
Hijab ZahraDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.
Asmat AliDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.
Mathias ToftDepartment of Neurology, Oslo University Hospital, Oslo 0424, Norway.
Marc DieuMaSUN-Proteomic Facility, Université de Namur, Namur 5000, Belgium.ORCID https://orcid.org/0000-0002-3902-542X
Younes AchouriTransgene Technology Platform TRSG, Université catholique de Louvain, Leuven 1348, Belgium.ORCID https://orcid.org/0000-0001-7409-1441
Meng LiNeuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, United Kingdom.
Patricia RenardMaSUN-Proteomic Facility, Université de Namur, Namur 5000, Belgium.
Carine Van LintService of Molecular Virology, Department of Molecular Biology and ULB-Cancer Research Centre, Université Libre de Bruxelles, Gosselies 6041, Belgium.
Coralie PoulardINSERM U1052, CNRS UMR5286, Université Claude Bernard Lyon1, Centre de Recherche en Cancérologie de Lyon, Lyon F-69000, France.
Zafar IqbalDepartment of Paediatrics and Child Health, Aga Khan University, Karachi 74800, Pakistan zafar.iqbal@ous-research.no Eric.Bellefroid@ulb.be.ORCID https://orcid.org/0000-0002-6387-8019
Eric J BellefroidLaboratory of Developmental Genetics, Department of Molecular Biology and ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Gosselies 6041, Belgium zafar.iqbal@ous-research.no Eric.Bellefroid@ulb.be.ORCID https://orcid.org/0000-0001-9975-5945

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dmrta2 (also designated Dmrt5) is a transcriptional regulator expressed in cortical progenitors in a caudomedial

Indexed as

Body PatterningCerebral CortexHomeodomain ProteinsMicrocephalyPAX6 Transcription FactorTranscription FactorsAnimalsDNAFemaleGene Expression Regulation, DevelopmentalHumansMiceMutationDNAHomeodomain ProteinsPAX6 protein, humanPax6 protein, mousePAX6 Transcription FactorTranscription Factorscerebral cortexmicrocephalyneural progenitorneurogenesispatterningtranscription factor

Identifiers

PMID40541527
PMCPMC12186615

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.