A Novel Approach for Cerebral Embolic Protection With Single-Artery Access in TAVR.

Isaac George, Maximilian Reisinger, Mateusz Kachel, Irakli Gogorishvili, Gvantsa Dughashvili, May Nour, Tamim M Nazif

Abstract readCase Reports

In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Isaac GeorgeDivision of Cardiac, Thoracic, and Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA; Structural Heart and Valve Center, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA. Electronic address: ig2006@cumc.columbia.edu.

Maximilian ReisingerDivision of Cardiac, Thoracic, and Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA.

Mateusz KachelDivision of Cardiac, Thoracic, and Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA; Center for Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland.

Irakli GogorishviliIsraeli-Georgian Medical Research Clinic Healthycore, Tbilisi, Georgia.

Gvantsa DughashviliIsraeli-Georgian Medical Research Clinic Healthycore, Tbilisi, Georgia.

May NoureHealth Merit Corporation, Los Angeles, California, USA.

Tamim M NazifStructural Heart and Valve Center, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral embolic protection devices (CEPDs) have been developed to decrease embolic brain injury and stroke during transcatheter aortic valve replacement (TAVR). Simplifying vascular access for a CEPD may increase procedural efficiency and safety FIRST-IN-HUMAN/EARLY REPORTS SUMMARY: This is the first published report of the use of the novel EnCompass F DISCUSSION: Cerebral protection was feasible and safe without device-related complications, clinical stroke, or other neurologic events. Postprocedural diffusion-weighted magnetic resonance imaging revealed only 1 very small, clinically insignificant new brain lesion. NOVELTY: This presents the first successful use of a CEPD in TAVR through access by a single femoral artery. TAKE-HOME MESSAGE: The use of the novel EnCompass F

Indexed as

cerebral embolic protection devicesingle-artery accessstroketranscatheter aortic valve replacement

Identifiers

PMID40541343

DOI10.1016/j.jaccas.2025.103768

PMCPMC12198642

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