Trial reportBMJ open respiratory research2025
Which clinical factors are predictive of outcome in primary spontaneous pneumothorax management?
Trial report in BMJ open respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary spontaneous pneumothorax (PSP) occurs when air leaks into the pleural space in patients without known underlying lung disease, causing pain and breathlessness. Optimal management of PSP is not defined and we are unable to predict who will fail medical treatment (ongoing pneumothorax with prolonged air leak). We hypothesised that patients with longer symptom duration and higher symptom scores would be more likely to fail treatment.
methodsProspectively collected data from the Randomised Ambulatory Management of Primary Pneumothorax randomised controlled trial of ambulatory management were used to determine which clinical factors are associated with treatment failure including symptom scores, time from symptom onset to presentation, treatment allocation, vital signs, history of prior pneumothorax and size of initial pneumothorax.
resultsOverall, 63/236 patients (26.7%) failed treatment. On average, symptoms started 1 day before admission. Multivariable analysis found that patients who presented at least 1 day after symptoms began had a lower risk of treatment failure than those presenting on the day symptoms began (ORs 0.39 (0.18 to 0.81)).
conclusionFurther work is required to determine psychological drivers of PSP presentation and risks of prolonged air leak.
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