Evidence map›Paper›PMID 40541247›Full record

Trial reportArquivos de neuro-psiquiatria2025

EMG versus US: a randomized clinical trial comparing the efficacy in guiding botulinum toxin treatment in cervical dystonia.

Mayara Thouin Graciani, Flávio Henrique de Rezende Costa, Ana Lucia Zuma de Rosso, Gil Fernando Salles

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mayara Thouin GracianiUniversidade Federal do Rio de Janeiro, Faculdade de Medicina, Departamento de Neurologia, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-3683-6307
Flávio Henrique de Rezende CostaUniversidade Federal do Rio de Janeiro, Faculdade de Medicina, Departamento de Neurologia, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-8801-9675
Ana Lucia Zuma de RossoUniversidade Federal do Rio de Janeiro, Faculdade de Medicina, Departamento de Neurologia, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-2545-715X
Gil Fernando SallesUniversidade Federal do Rio de Janeiro, Faculdade de Medicina, Departamento de Medicina Interna, Rio de Janeiro RJ, Brazil.ORCID 0000-0001-6318-7077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Botulinum toxin type A (BoNT-A) is considered the first-line therapy for cervical dystonia.To compare, in a randomized trial, the efficacy of treatment with BoNT-A guided by ultrasound (US) and electromyography (EMG) in patients with idiopathic cervical dystonia.A total of 40 patients (20 in each group; mean age: 54 years; 45% of female subjects; mean disease duration: 10.7 years) were randomized to either US- or EMG-guided BoNT-A treatment. The efficacy of BoNT-A was assessed through changes in the scores on the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) before and 4 to 6 weeks after the treatment. The differences in the absolute and relative changes in the total TWSTRS scores and in its components (severity, incapacity, and pain) between the groups were evaluated.The US and EMG groups were well balanced in relation to baseline and demographic characteristics. After the BoNT-A treatment, there was a mean reduction in the TWSTRS score of 8 points (relative reduction of 23%) equally between the US and EMG groups (mean difference in absolute decrease of 0.1 point;

Indexed as

Botulinum Toxins, Type AElectromyographyNeuromuscular AgentsTorticollisUltrasonography, InterventionalAdultAgedFemaleHumansMaleMiddle AgedSeverity of Illness IndexTreatment OutcomeBotulinum Toxins, Type ANeuromuscular Agents

Identifiers

PMID40541247
PMCPMC12180953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.