Evidence map›Paper›PMID 40541243›Full record

ArticleArquivos de neuro-psiquiatria2025

The impact of multiple sclerosis on wellbeing, productivity, and societal relations.

Vinicius Eduardo Vergani, Bruna Rocha Silveira, Gustavo San Martin Elexpe Cardoso, Jean Faber, Denis Bernardi Bichuetti

Abstract read
In one paragraph

Article in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vinicius Eduardo VerganiUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo SP, Brazil.ORCID 0000-0001-5149-2306
Bruna Rocha SilveiraAmigos Múltiplos pela Esclerose, Guarulhos SP, Brazil.ORCID 0000-0003-3418-7603
Gustavo San Martin Elexpe CardosoAmigos Múltiplos pela Esclerose, Guarulhos SP, Brazil.ORCID 0000-0001-6926-3392
Jean FaberUniversidade Federal de São Paulo, Escola Paulista de Medicina, Disciplina de Neurociências, São Paulo SP, Brazil.ORCID 0000-0002-2129-8251
Denis Bernardi BichuettiUniversidade Federal de São Paulo, Escola Paulista de Medicina, Disciplina de Neurologia, São Paulo SP, Brazil.ORCID 0000-0002-4011-3734

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is the main cause of nontraumatic neurological disabilities in the population under 50 years of age.To evaluate the most prevalent symptoms in a national sample of people with MS and to analyze their correlation with disease characteristics, demographics, quality of life, employment status, and use of social benefits.Cross-sectional, online, self-reported survey, concerning demographic and clinical data, employment status, and use of social benefits.A total of 466 patients answered the survey. The median age at onset was 30 years, the current age, of 39, and disease duration was 8 years. Furthermore, the median patient determined disease steps (PDDS) was 2, which indicates minor to moderate disability. The median MS impact and walking scale scores were 31 and 20%, which denotes minor to moderate quality of life and mobility compromise. Among the participants, 43% suffered fatigue and 51% reported not sleeping well. Unemployed patients had delayed diagnosis and higher disability rates. Furthermore, half of the unemployed patients are receiving some social benefit, compared with only 6.5% of the employed patients.The current study presents symptom prevalence in a national sample of patients with MS and discloses that those with a diagnosis delay and more disability have higher rates of unemployment and use of social benefits. Strategies for earlier diagnosis and better treatment plans can not only reduce patient disability but, possibly, increase employment retention and reduce the use of social benefits.

Indexed as

EfficiencyMultiple SclerosisQuality of LifeAdultBrazilCross-Sectional StudiesDisability EvaluationEmploymentFemaleHumansMaleMiddle AgedSeverity of Illness IndexSocioeconomic FactorsSurveys and QuestionnairesUnemployment

Identifiers

PMID40541243
PMCPMC12180951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.