ArticleCurrent biology : CB2025
Divergent synaptic dynamics originate parallel pathways for computation and behavior in an olfactory circuit.
Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Undoing of firing rate adaptation enables invariant population codes.Science advances · 2026Article
- Sensory processing reformats odor coding around valence and dynamics.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
To enable diverse sensory processing and behavior, central circuits use divergent connectivity to create parallel pathways. However, linking synaptic and cellular mechanisms to the circuit-level segregation of computation has been challenging. Here, we investigate the generation of parallel processing pathways in the Drosophila olfactory system, where glomerular projection neurons (PNs) diverge onto many lateral horn neurons (LHNs). We compare the effects of a single PN's activity on two of its target LHNs. One LHN type generates sustained responses to odor and adapts divisively. The other generates transient responses and adapts subtractively. The distinct odor-coding dynamics originate from differences in the dynamics of PN synapses targeting each LHN type. Sustained LHN responses arise from synapses that recover from depression quickly enough to maintain ongoing transmission. Divisive adaptation is due to slow cellular gain control implemented by the Na
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.