Evidence map›Paper›PMID 40540790›Full record

ReviewCurrent opinion in chemical biology2025

Recent advances in metallophore research uncover functions in quorum sensing, antimicrobial activity, and lanthanide acquisition.

Ghazal Kamyabi, Erica L Debley, Elizabeth M Nolan

Abstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Prevalence and Antimicrobial Resistance ofInfectious disease reports · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ghazal KamyabiDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Erica L DebleyDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Elizabeth M NolanDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: lnolan@mit.edu.

Funding

Harnessing iron acquisition to hinder enterobacterial pathogenesisR01AI176390 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth M Nolan, Manuela Raffatellu · 2023 to 2026
$2.9M
Metallobiochemistry of innate immunity and bacterial physiologyR01GM126376 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NOLAN, ELIZABETH M, OGLESBY, AMANDA GAIL · 2017 to 2024
$2.4M
Bioinorganic Explorations of Host-Defense ProteinsR01GM118695 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NOLAN, ELIZABETH M · 2017 to 2025
$2.3M
Proyecto Tariki: Implementation Science for Community-Mobilized Risk Reduction of DengueR01AI176380 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI Valerie Andrea Paz-Soldan · 2024 to 2026
$1.9M
NIAID NIH HHS R01 AI176380NIAID NIH HHS R01 AI176390NIGMS NIH HHS R01 GM118695NIGMS NIH HHS R01 GM126376
6 · The paper itself

Abstract

Metallophores are metal-chelating secondary metabolites that bacteria, fungi, and other organisms produce to acquire essential metal nutrients from their environment. This review highlights some recent discoveries in the field: the role of yersiniabactin in quorum sensing, the capacity of aspergillomarasmine A to inhibit bacterial Ni uptake, and the identification of methylolanthanin, a novel metallophore that enables bacterial lanthanide acquisition.

Indexed as

Anti-Infective AgentsLanthanoid Series ElementsQuorum SensingAnimalsHumansMethylationNickelAnti-Infective AgentsLanthanoid Series ElementsNickel

Identifiers

PMID40540790
PMCPMC13499598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.