Evidence map›Paper›PMID 40540776›Full record

ArticleDrug and alcohol dependence2025

Reliability and clinical utility of heroin craving questionnaire factors in treatment-enrolled individuals with opioid use disorder.

April C May, Breanna A McNaughton-Long, Chrysantha B Davis, Abigail J Pleiman, Carmen Buchfink, Rayus Kuplicki, Hung-Wen Yeh, Martin P Paulus, Jennifer L Stewart

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

April C MayUniversity of California, San Diego, Department of Psychiatry, United States. Electronic address: acmay@health.ucsd.edu.
Breanna A McNaughton-LongLaureate Institute for Brain Research, United States.
Chrysantha B DavisLaureate Institute for Brain Research, United States.
Abigail J PleimanLaureate Institute for Brain Research, United States.
Carmen BuchfinkLaureate Institute for Brain Research, United States.
Rayus KuplickiLaureate Institute for Brain Research, United States.
Hung-Wen YehHealth Services & Outcomes Research, Children's Mercy Research Institute, Kansas City, MO, United States; University of Missouri Kansas City School of Medicine, Kansas City, MO, United States.
Martin P PaulusLaureate Institute for Brain Research, United States; Oxley College of Health and Natural Sciences, University of Tulsa, United States.
Jennifer L StewartLaureate Institute for Brain Research, United States; Oxley College of Health and Natural Sciences, University of Tulsa, United States.

Funding

The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)P20GM121312 · NIGMS · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI MARTIN P. PAULUS · 2017 to 2026
$23.7M
Fellowship on Biological Psychiatry and NeuroscienceT32MH018399 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pei-an (Betty) Shih · 1986 to 2026
$7.3M
Plasticity of Aversive Salience in Opioid Use DisorderR01DA050677 · NIDA · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI STEWART, JENNIFER LORRAINE · 2021 to 2025
$3.0M
NIDA NIH HHS R01 DA050677NIGMS NIH HHS P20 GM121312NIMH NIH HHS T32 MH018399
6 · The paper itself

Abstract

Psychometric properties of opioid craving assessments are underexamined, limiting their potential utility for treatment studies of opioid use disorder (OUD). To address this gap, the current study aimed to evaluate the predictive utility of the Heroin Craving Questionnaire (HCQ) for future substance use outcomes. Treatment-enrolled participants with OUD (n = 128) completed the Heroin Craving Questionnaire (HCQ) at baseline and were followed up to assess future return to use versus abstinence. Individuals who maintained abstinence at each of three follow-up visits also completed the HCQ again. Exploratory factor analysis (EFA) was performed on baseline HCQ items, and extracted factors were evaluated for: (1) internal consistency reliability (Cronbach's alpha); (2) associations with demographic and clinical variables; (3) follow-up group differences; (4) test-retest reliability (intraclass coefficients: ICCs); and (5) change across visits. EFA results produced a three-factor structure, retaining 30 of 45 HCQ items and accounting for 54.60 % of the variance: (1) Lack of Self-Control (10 items, alpha=.93); (2) Positive Expectancies (11 items, alpha=.91); and (3) Urgency (9 items, alpha=.89). Results indicated that: (1) elevated scores on all three factors were associated with comorbid amphetamine use disorder; (2) higher Lack of Self-Control and Positive Expectancies scores related to fewer days since last heroin use; (3) greater Lack of Self-Control and Urgency scores were associated with higher anxiety severity; and (4) ICCs showed moderate to good test-retest reliability between baseline and follow-up visits. However, factor scores at baseline could not differentiate future relapsers versus abstainers. More research is warranted to replicate these factors in additional OUD samples.

Indexed as

CravingHeroinHeroin DependenceOpioid-Related DisordersAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedOpiate Substitution TreatmentPsychometricsReproducibility of ResultsSurveys and QuestionnairesYoung AdultHeroinClinical utilityCravingHeroin craving questionnaireOpioid use disorderPsychometrics

Identifiers

PMID40540776
PMCPMC12664305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.