Evidence map›Paper›PMID 40540633›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Epigenome-Wide Analysis Identifies Pollution-Sensitive Loci in Fibrotic Interstitial Lung Disease.

Gillian C Goobie, Najmeh Assadinia, Chen Xi Yang, Fanny Chu, Rachel L Clifford, Joel D Cooper, James P Fabisiak, Kevin F Gibson, Kerri A Johannson, Daniel J Kass and 11 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. From Smog to Scar: Epigenetic Signatures of Air Pollution in Interstitial Lung Disease.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Gillian C GoobieDivision of Respiratory Medicine, Department of Medicine, and.ORCID 0000-0001-7982-5635
Najmeh AssadiniaCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Chen Xi YangCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Fanny ChuCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Rachel L CliffordFaculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0002-8677-452X
Joel D CooperDivision of Thoracic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
James P FabisiakDepartment of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0003-0283-8985
Kevin F GibsonDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.
Kerri A JohannsonDivision of Respiratory Medicine, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-1205-5511
Daniel J KassDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0001-6597-7830
Sharon E KimDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.
Xiaoyun LiDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0003-0000-9171
Kathleen O LindellCollege of Nursing, Medical University of South Carolina, Charleston, South Carolina.ORCID 0000-0002-2927-0659
Daniel-Costin MarinescuDivision of Respiratory Medicine, Department of Medicine, and.ORCID 0000-0003-3358-7699
Dragos M VasilescuCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.ORCID 0000-0003-3936-4365
Victoria WangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.
Christopher CarlstenDivision of Respiratory Medicine, Department of Medicine, and.
S Mehdi NouraieDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0001-7465-0581
Christopher J RyersonDivision of Respiratory Medicine, Department of Medicine, and.
Tillie L HackettDepartment of Anaesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-7134-3287
Yingze ZhangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0001-6947-2901

Funding

High-Throughput Computing for Genomics and Bioinformatics ResearchS10OD028483 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEE, ADRIAN V · 2021 to 2021
$574k
Boehringer Ingelheim 1199-0439NIH HHS S10 OD028483
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureEpigenomeLung Diseases, InterstitialParticulate MatterAgedCohort StudiesDNA MethylationEpigenesis, GeneticFemaleHumansMaleMiddle AgedRetrospective StudiesAir PollutantsParticulate Matterair pollutionDNA methylationepigeneticsinterstitial lung diseaseparticulate matter

Identifiers

PMID40540633
PMCPMC12555053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.