Evidence map›Paper›PMID 40540603›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Gut microbiome and host TOR pathway interact to regulate predator-induced aversive memory in

Hao-Yu Chen, Po-Sheng Wu, Zong-You Li, You-Cheng Liu, Sheng-Rong Yeh, Bi-Chun Duan, Kai-Wen Cheng, Cheng-Chih Hsu, Yen-Ling Chiu, Wang-Tso Lee and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Is it time to assignApplied and environmental microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hao-Yu Chen *Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Po-Sheng Wu *Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Zong-You Li *Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
You-Cheng LiuGraduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Sheng-Rong YehGraduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0009-0007-7000-1593
Bi-Chun DuanGraduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Kai-Wen ChengDepartment of Chemistry, National Taiwan University, Taipei 106, Taiwan.ORCID 0000-0002-6717-4342
Cheng-Chih HsuDepartment of Chemistry, National Taiwan University, Taipei 106, Taiwan.ORCID 0000-0002-2892-5326
Yen-Ling ChiuDivision of Nephrology, Department of Medicine, Far Eastern Memorial Hospital, Taipei 220, Taiwan.
Wang-Tso LeeGraduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0003-3231-9764
Shou-Zen FanDepartment of Anesthesiology, National Taiwan University Hospital, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0002-6849-8453
Pei-Yu WangGraduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0002-1792-8935

Funding

National Health Research Institutes (NHRI) NHRI-12A1-CG-CO-08-2325-2National Science and Technology Council (NSTC) 111-2320-B-002-018 112-2320-B-002-026 113-2321-B-418-005 113-2320-B-002-021-MY3National Science and Technology Council (NSTC) 113-2321-B-418-005National Taiwan University () 112L895401National Taiwan University Hospital (NTUH) 113-UN0065
6 · The paper itself

Abstract

The gut microbiome has emerged as a key factor influencing a wide range of host physiological processes and behaviors, though the mechanisms behind these effects remain only partially understood. In this study, we explored the role of the gut microbiome in memory regulation using a parasitoid wasp-induced oviposition depression paradigm in

Indexed as

Drosophila melanogasterDrosophila ProteinsGastrointestinal MicrobiomeMemoryTOR Serine-Threonine KinasesAcetobacterAmino Acids, Branched-ChainAnimalsAnti-Bacterial AgentsFemaleLactiplantibacillus plantarumOvipositionSignal TransductionAmino Acids, Branched-ChainAnti-Bacterial AgentsDrosophila Proteinstarget of rapamycin protein, DrosophilaTOR Serine-Threonine Kinasesgut microbiomememoryTOR

Identifiers

PMID40540603
PMCPMC12207471

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.