ArticleScience advances2025
A magnetically actuated microcatheter with soft rotatable tip for enhanced endovascular access and treatment efficiency.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The trial behind it
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Who cites it
14 citing papers in PubMed.
- A ciliated intravascular soft millirobot for multimodal in-flow collective manipulation.Science advances · 2026Article
- 3D-printed chiral luminous materials.Nature communications · 2026Article
- Physics-constrained learning framework for trustworthy microrobot navigation autonomy.Science advances · 2026Article
- Soft robotic devices for cardiovascular medicine.Nature reviews. Cardiology · 2026Review
- The Heart's Electromagnetic Field in Emotions, Empathy and Human Connection: Biosensor-Derived Insights into Heart-Brain Axis Mechanisms and a Basis for Novel BioMagnetoTherapies.Sensors (Basel, Switzerland) · 2026Review
- Chitosan and polycaprolactone blended PDMS coatings improve biocompatibility of magnetic elastomers.Scientific reports · 2026Article
- Bio-Inspired Micro-Fin-Assisted Multi-Modal Vascular Intervention.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Machine learning guided stimuli-responsive catheter for directional drug delivery and dynamic biliary state recognition.Materials today. Bio · 2026Article
- Micro/Nanorobotic Systems for Imaging-Guided Closed-Loop Thrombus Recanalization.Cyborg and bionic systems (Washington, D.C.) · 2026Review
- Magnetically controlled microrobotic system for programmable stiffness tuning and active steering of microcatheters.Nature communications · 2025Article
- Advancements and challenges in autonomous endovascular interventional robotics: A comprehensive review.iScience · 2025Review
- Stable magnetic soft structures.Science advances · 2025Article
- Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Magnetic slippery microcatheter with artificial cilia for low-friction interventions.Science advances · 2025Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endovascular interventions require fast access to affected regions, followed by effective treatment. Catheterizations are effective approaches for treating vascular diseases; however, they face challenges in accessibility, efficiency, and invasiveness in narrow, tortuous vascular systems. This study presents a submillimeter magnetically actuated soft rotatable-tipped microcatheter (MSRM) designed to access small blood vessels and provide efficient, minimally invasive therapeutic interventions for blood clot treatment. The MSRM's rotatable tip design enhances accessibility and navigation speed through a rotation-assisted active steering strategy. Improved blood clot treatment efficiency is achieved through the MSRM's multifunctionality: It can accelerate drug-blood clot interactions, mechanically break down blood clots, and retrieve clot debris. The low invasiveness is attributed to the soft material design and conservative actuation strategy. The performance of the MSRM is validated in both in vitro phantom studies and in vivo rabbit models, and the invasiveness is evaluated using a human placenta model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.