ArticlePloS one2025
Design of Polyether sulfone flat-sheet membranes for multi-layered hemodiafiltration devices.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Multilayered hemodialysis devices enable blood flow without the need for an external pump, whereas hollow fiber-type devices require a pump due to significant pressure loss across the fibers. This highlights a key advantage of multilayered devices for implantable applications, where a simpler and lighter system reduces the burden on patients. This study investigates the mechanical strength and dialysis efficiency of polyether sulfone (PES) flat-sheet membranes for multilayered devices. PES membranes, with thicknesses ranging from 40 to 160 µm, were prepared using the liquid inversion method, with thickness controlled via spin coating. The mechanical strength of the membranes was tested following the ISO 8637-1:2017 protocol, and membranes thicker than 80 µm were experimentally verified to withstand pressures of up to 500 mmHg, making them suitable for dialysis applications. Furthermore, the study demonstrates the successful use of 80 µm membranes in both in vitro and ex vivo experiments with rats, identifying this thickness as optimal for multilayered dialysis devices.
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