ArticleInternational ophthalmology2025
Effect of preoperative antiglaucoma medication duration on surgical outcomes of gonioscopy-assisted transluminal trabeculotomy in open-angle glaucoma.
Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the impact of preoperative antiglaucoma medication duration on the surgical outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in patients with open-angle glaucoma (OAG).
designRetrospective comparative study. PATIENTS AND
methodsThis retrospective case series included 64 eyes from patients diagnosed with primary OAG or pseudoexfoliative glaucoma who underwent 360-degree GATT. Patients were categorized into three groups based on the duration of preoperative medication use: short-term (< 2 years), moderate-term (2-5 years), and long-term (> 5 years). Intraocular pressure (IOP) was measured using Goldmann applanation tonometry during follow-up visits, and surgical success was defined based on IOP reduction criteria. The number of glaucoma medications, best-corrected visual acuity, and postoperative complications were also recorded. Kaplan-Meier survival analysis was used to assess success rates.
resultsThe mean follow-up duration was 17.2 ± 6.8 months. The short-term, moderate-term, and long-term groups achieved significant IOP reductions (p < 0.001), with final mean IOPs of 13.2 ± 4.7 mmHg, 17.7 ± 6.4 mmHg, and 18.1 ± 6.9 mmHg, respectively (p = 0.002). The mean number of postoperative medications decreased significantly across all groups (p = 0.032). Qualified success rates were 92.3%, 77.2%, and 79.3% for the short-term, moderate-term, and long-term groups, respectively, while complete success rates were 76.9%, 63.6%, and 58.6%.
conclusionGATT effectively lowers IOP in patients with OAG, though prolonged preoperative medication use is associated with reduced surgical success and higher postoperative medication dependence. Early surgical intervention may enhance long-term outcomes for patients with a history of escalating medication regimens.
Indexed as
Identifiers
40540049What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.