Evidence map›Paper›PMID 40540041›Full record

SynthesisClinical and experimental medicine2025

Global and regional prevalence of osteoporosis in kidney transplant recipients: a systematic review and meta-analysis.

Mobin Ghazaiean, Tahoora Mousavi, Mahmood Moosazadeh

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mobin GhazaieanStudent Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.ORCID http://orcid.org/0000-0001-9240-494X
Tahoora MousaviMolecular and Cell Biology Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran. stm.jmums@gmail.com.ORCID http://orcid.org/0000-0003-2505-370X
Mahmood MoosazadehGastrointestinal Cancer Research Center, Non-Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran. mmoosazadeh1351@gmail.com.ORCID http://orcid.org/0000-0002-5452-514X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney transplant recipients (KTRs) are at a heightened risk of low bone density and fractures. This study sought to determine the overall prevalence of osteoporosis in KTRs. Published observational studies and those with a baseline report on osteoporosis were evaluated in databases such as PubMed, Scopus, Science Direct, Web of Science, and EMBASE, in addition to Google Scholar from January 1, 2000, to January 1, 2024. The methodological quality of the included studies was rigorously assessed using the JBI Critical Appraisal checklist. Heterogeneity across primary study results was evaluated using the I-square index, while publication bias was scrutinized using Egger's test and funnel plots. Statistical analyses were carried out using Stata software Ver. 11. After conducting searches across multiple databases, a total of 136 primary studies were ultimately included. The prevalence of osteoporosis in specific skeletal areas is as follows: 20% (95% CI 18-23, n = 67) in the lumbar region, 23% (95% CI 19-26, n = 53) in the femoral neck, 15% (95% CI 11-19, n = 20) in the total hip, 29% (95% CI 10-49, n = 5) in the forearm, and 34% (95% CI 28-40, n = 6) in the ultradistal radius. Based on sex-specific rate in the existing literature, the prevalence is reported as 21% (95% CI 15-27, n = 16) in men and 28% (95% CI 20-35, n = 16) in women. Our results for adult KTRs represent the high prevalence of osteoporosis which was highest in bone site rich in cortical content (e.g., ultradistal radius).

Indexed as

Kidney TransplantationOsteoporosisTransplant RecipientsBone DensityFemaleHumansMaleMiddle AgedPrevalenceAdultEpidemiologyKidney transplant recipientsOsteoporosisPrevalence

Identifiers

PMID40540041
PMCPMC12181100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.