ArticlePediatric cardiology2026
Do Hemodynamic and Echocardiographic Derangements After the Fontan Operation Correlate with Severity of Liver Disease on Biopsy?
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Liver biopsy remains the gold standard for evaluating Fontan-associated liver disease. Prior studies show that unfavorable Fontan hemodynamics are associated with a higher risk of developing liver disease. We sought to determine whether hemodynamics pre- and post-Fontan, severity of atrioventricular valve regurgitation (AVV), and systemic ventricular dysfunction by echocardiography correlate with the degree of liver disease on biopsy. In this single-center retrospective study, we included patients with Fontan physiology who had a liver biopsy between January 2008 and May 2024. Pre- and post-Fontan catheterization data, as well as post-Fontan echocardiogram data, were reviewed. Severity of liver fibrosis was classified by the congestive hepatic fibrosis score. Data was analyzed using dichotomization (low grade score 0-2B and high grade 3-4) with χ
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