Evidence map›Paper›PMID 40539937›Full record

ArticleActa crystallographica. Section C, Structural chemistry2025

Standards for MicroED.

Johan Unge, Brent L Nannenga, Allen G Oliver, Tamir Gonen

Abstract read
In one paragraph

Article in Acta crystallographica. Section C, Structural chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Semi-automated MicroED system unveils multiple polymorphs in fish-derived guanine crystals.Acta crystallographica. Section C, Structural chemistry · 2026
    Article
  2. Membrane protein structure and dynamics probed by MicroED.Biochemical Society transactions · 2026
    Review
  3. Rapid Structural Analysis of Natural Products Using MicroED.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Johan UngeDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.
Brent L NannengaChemical Engineering, School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, USA.
Allen G OliverMolecular Structure Facility, 149 Stepan Chemistry Hall, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID 0000-0002-0511-1127
Tamir GonenHoward Hughes Medical Institute, University of California, Los Angeles, Los Angeles 90095, USA.

Funding

TRD4: Design and Engineering of MicroED hardware for nanocrystallization and time resolved studiesP41GM136508 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GONEN, TAMIR, NANNENGA, BRENT · 2020 to 2024
$7.6M
MEDIC-MicroED Imaging Center at UCLARM1GM158451 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Tamir Gonen, Brent Nannenga · 2025 to 2026
$2.7M
Department of Defense HDTRA1-21-1-0004Department of Defense MCDC-2202-002NIGMS NIH HHS P41 GM136508NIGMS NIH HHS P41GM136508NIGMS NIH HHS RM1 GM158451
6 · The paper itself

Abstract

As the electron diffraction technique MicroED gains momentum and is increasingly embraced by researchers in both academia and industry, we have the opportunity to familiarize ourselves with the characteristics of MicroED data and results. The number of refined structures and their associated data is steadily growing and becoming more accessible to the scientific community, offering valuable insights into the significance and quality of MicroED-derived structures. Additionally, the growing body of experience is helping to identify best practices for the technique. In this summary, we highlight key lessons learned from these data and propose gold standards for the community to consider adopting.

Indexed as

Microscopy, Electron, TransmissionElectronsbest practicescryoEMelectron diffractionGold standardsMicroEDquality indicator

Identifiers

PMID40539937
PMCPMC12231505

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.