Evidence map›Paper›PMID 40539832›Full record

ArticleJournal of clinical microbiology2025

Performance and workflow comparison of the VITEK MS PRIME and Bruker Biotyper MALDI-TOF MS systems.

Rachel E Bosserman, Nicole J Tarlton, Kelly Alvarado, Brittany Roemmich, Melanie L Yarbrough

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Evaluation of the VITEKEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel E BossermanDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Nicole J TarltonDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Kelly AlvaradoDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Brittany RoemmichDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Melanie L YarbroughDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-2166-7552

Funding

bioMérieux SA n/a
6 · The paper itself

Abstract

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is widely used for rapid identification of bacteria and yeast in clinical labs. The VITEK MS PRIME ("PRIME") is the latest MALDI-TOF MS system from bioMérieux. This study evaluated PRIME's performance and workflow timing against the MALDI Biotyper CA System by Bruker ("Biotyper"). We compared a collection of 154 bacteria and yeast clinical isolates from various specimen types using three methods: Biotyper target with a toothpick, PRIME target with the PICKME nib, and PRIME target with a loop. Positive blood culture isolates were also analyzed using these methods, with high-experience (HEU,

Indexed as

BacteriaSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationWorkflowYeastsBacterial InfectionsHumansTime FactorsMALDI BiotyperMALDI-TOF MSVITEK MS PRIME

Identifiers

PMID40539832
PMCPMC12345239

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.