Evidence map›Paper›PMID 40539815›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2025

Implications of morphological variation in influenza viruses.

Chidiebere F Uchechukwu, Nicole C Robb

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chidiebere F UchechukwuWarwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0009-0008-3433-9332
Nicole C RobbWarwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0002-7740-6629

Funding

Biotechnology and Biological Sciences Research Council BB/T00746X/1Royal Society DKR00620
6 · The paper itself

Abstract

SUMMARYPleomorphism in influenza viruses, characterized by diverse morphological forms ranging from spherical virions to elongated filaments, has been suggested to present significant implications for pathogenesis. This review examines the role of pleomorphism on the influenza virus life cycle, encompassing viral attachment and entry, replication, assembly, and budding, as well as transmission dynamics. It explores the determinants' underlying morphological variability in virions and their impact on viral fitness and host interactions. Insights into how pleomorphic forms of the virus influence disease severity and the efficacy of antivirals are discussed. Understanding the implications of pleomorphism in influenza virus pathogenesis is crucial for the development of effective disease prevention, control, and treatment strategies.

Indexed as

Influenza, HumanOrthomyxoviridaeAnimalsAntiviral AgentsHost-Pathogen InteractionsHumansVirionVirus AssemblyVirus AttachmentVirus InternalizationVirus ReplicationAntiviral Agentsantiviralsbacilliformfilamentoushost-virus interactionsinfluenza virus morphologypathogenesisspherical

Identifiers

PMID40539815
PMCPMC12462282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.