Evidence map›Paper›PMID 40539790›Full record

ArticlemBio2025

Carlton O Adams, Jackson A Campbell, Beichang Zhang, Leanne Cleaver, Sarah B Bier, Joshua Mayoral, Richard C White, James A Garnett, Nicholas P Cianciotto

Erratum issuedAbstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Mucin stimulates the growth ofMicrobiology (Reading, England) · 2026
    Article
  5. Article
  6. Molecular evolution and adaptations ofFrontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Carlton O AdamsDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Jackson A CampbellDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Beichang ZhangCentre for Host-Microbiome Interactions, Faculty of Dental, Oral & Craniofacial Sciences, King's College London, London, United Kingdom.
Leanne CleaverCentre for Host-Microbiome Interactions, Faculty of Dental, Oral & Craniofacial Sciences, King's College London, London, United Kingdom.ORCID 0000-0002-7788-9384
Sarah B BierDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Joshua MayoralDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Richard C WhiteDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
James A GarnettCentre for Host-Microbiome Interactions, Faculty of Dental, Oral & Craniofacial Sciences, King's College London, London, United Kingdom.ORCID 0000-0001-7621-8223
Nicholas P CianciottoDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.ORCID 0000-0002-9572-8322

Funding

TRAINING PROGRAM IN IMMUNOLOGY &MOLECULAR PATHOGENESIST32AI007476 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Edward Benjamin Thorp · 1996 to 2026
$6.6M
TYPE II SECRETION AND LEGIONELLA PNEUMOPHILA INFECTIONR01AI043987 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 1999 to 2017
$4.8M
Mucinases as Emerging Players in Legionella pneumophila PathogenesisR21AI175460 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 2023 to 2024
$420k
Importance and function of highly conserved substrates of the Legionella pneumophila Type II Secretion System for InfectionF31AI172194 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ADAMS, CARLTON · 2023 to 2024
$97k
Medical Research Council MR/R017662/1, MR/W000814/1National Institute of Allergy and Infectious Diseases AI007476, AI172194National Institute of Allergy and Infectious Diseases AI043987, AI175460NIAID NIH HHS F31 AI172194NIAID NIH HHS R01 AI043987NIAID NIH HHS R21 AI175460NIAID NIH HHS T32 AI007476Wellcome Trust CC1078
6 · The paper itself

Abstract

Prior analyses suggested that the type II secretion system (T2SS) of

Indexed as

AmidohydrolasesAnti-Bacterial AgentsBiofilmsLegionella pneumophilaPolymyxinsType II Secretion SystemsBacterial ProteinsBlood Bactericidal ActivityDrug Resistance, BacterialHumansAmidohydrolasesAnti-Bacterial AgentsBacterial ProteinsPolymyxinspolysaccharide deacetylaseType II Secretion Systemsautoaggregationbiofilm formationintracellular infectionlipopolysaccharideL. pneumophilaPdaApolysaccharide deacetylaseresistance to polymyxin Bserum-resistanceT2SS

Identifiers

PMID40539790
PMCPMC12239567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.