Evidence map›Paper›PMID 40539743›Full record

ArticleClinical and translational science2025

Effect of Whole-Brain Radiotherapy Dose on the Occurrence of Otitis Media and Mastoiditis in Patients With Lung Cancer With Brain Metastasis.

Xudong Zhang, Ying Huang, Hongfei Li, Yuntong Pei, Fanyang Kong, Qian Zhang, Yadong Song, Yunji Wang, Guowen Li

Abstract read
In one paragraph

Article in Clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xudong ZhangDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0009-0009-2771-5472
Ying HuangDepartment of Magnetic Resonance, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.ORCID 0009-0005-4155-483X
Hongfei LiDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0009-0005-3202-057X
Yuntong PeiDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0009-0008-2666-8013
Fanyang KongDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0009-0006-8529-9807
Qian ZhangDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0009-0009-5699-1927
Yadong SongDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0000-0002-3067-5039
Yunji WangDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0009-0006-3279-5268
Guowen LiDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0009-0003-2178-2689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate the incidence of acute mastoiditis in patients with brain metastases undergoing whole-brain radiotherapy (WBRT). A retrospective analysis was conducted on patients with brain metastases who received different doses of WBRT. The incidence of acute mastoiditis within 6 months post-radiotherapy was observed. Patients were divided into four groups based on the radiation dose: 25, 30, 36 and 40 Gy. The incidence of mastoiditis in each group was statistically analyzed. A total of 209 patients were followed up, with no cases lost to follow-up, and the follow-up time was 6 months. The results showed that the number of patients with middle ear mastoiditis was 6 (24%) in group A, 101 (67%) in group B, 12 (80%) in group C and 15 (83%) in group D, and there was a statistically significant difference between the four groups (χ

Indexed as

Brain NeoplasmsCranial IrradiationLung NeoplasmsMastoiditisOtitis MediaRadiation InjuriesAdultAgedDose-Response Relationship, RadiationFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedRadiotherapy Dosageacute mastoiditisbrain metastasesradiation doseradiotherapy complicationswhole‐brain radiotherapy

Identifiers

PMID40539743
PMCPMC12180080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.