Evidence map›Paper›PMID 40539333›Full record

ArticleOrthopaedic surgery2025

Predicting the Nonunion of the Acute Osteoporotic Vertebral Compression Fracture Following Low-Energy Injuries by Quantifying Vertebral Marrow Fat Fraction on T

Pengguo Gou, Rui Wang, Zhihui Zhao, Yunguo Wang, Yuan Xue

Abstract read
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Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Pengguo GouDepartment of Orthopedic Surgery, Tianjin Medical University General Hospital, Tianjin, China.ORCID https://orcid.org/0000-0002-0315-8941
Rui WangDepartment of Orthopedic Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Zhihui ZhaoDepartment of Orthopedic Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yunguo WangDepartment of Orthopedic Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yuan XueDepartment of Orthopedic Surgery, Tianjin Medical University General Hospital, Tianjin, China.ORCID https://orcid.org/0000-0003-4232-8146

Funding

Key Program of Tianjin Natural Science Foundation 20JCZDJC00310Shanxi Province Basic Research Project Foundation 202203021221264The National Natural Science Foundation of China 81871124
6 · The paper itself

Abstract

objectiveIncreased marrow fat fraction (MFF) of vertebrae was detected in patients with osteoporosis. However, MFF of the fractured vertebrae decreased significantly following the fracture. The aim of this study was to assess the predictive value of fractured vertebrae MFF quantified on T MATERIALS AND

methodsMedical records of 39 patients with OVCF, including a total of 60 fractured vertebrae, were reviewed retrospectively. Fractured vertebrae in the acute phase were grouped into the nonunion group (20 vertebrae) and the union group (40 vertebrae), based on the OVCF prognosis confirmed by computer tomography (CT). MFF of the fractured vertebrae was quantitatively assessed with the software Matlab on T

resultsThe ICC indicated that the repeatability of MFF measurement was excellent (all p < 0.001). The MFF (42.25% ± 26.61%) decreased significantly compared to the value before OVCF (79.84% ± 9.65%) (p < 0.001). The MFF of the fractured vertebrae was lower in the nonunion group (16.40% ± 15.65%) than in the union group (55.18% ± 20.93%) (p < 0.001). Binary logistic regression analysis indicated that MFF of fractured vertebrae could independently predict the prognosis of acute OVCF (p < 0.001). ROC analysis indicated the area under the curve was 0.928 (95% CI, 0.831-0.979, p < 0.0001).

conclusionsThe MFF quantified on T

Indexed as

Adipose TissueBone MarrowFractures, CompressionFractures, UnunitedMagnetic Resonance ImagingOsteoporotic FracturesSpinal FracturesAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective Studiesfracturemagnetic resonance imagingmarrow fat fractionnonunionosteoporosis

Identifiers

PMID40539333
PMCPMC12318669

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.