Evidence map›Paper›PMID 40539308›Full record

ArticleChemSusChem2025

Microfluidic-Assisted Evolution of a Robust NAD

Mariko Teshima, Robert Genth, Tenuun Bayaraa, Manuel Döring, Barbara Beer, Gerhard Schenk, Volker Sieber

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemSusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariko TeshimaChair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany.
Robert GenthChair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany.
Tenuun BayaraaChair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany.
Manuel DöringChair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany.
Barbara BeerChair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany.
Gerhard SchenkSchool of Chemistry and Molecular Biosciences, The University of Queensland, 68 Cooper Rd, St. Lucia, Brisbane, 4072, Australia.
Volker SieberChair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany.ORCID 0000-0001-5458-9330

Funding

Deutsche Forschungsgemeinschaft
6 · The paper itself

Abstract

Prompted by the thermostability issue identified in recent work on enzyme discovery/engineering and its application, the directed evolution of an NAD

Indexed as

Aldehyde DehydrogenaseButanolsDirected Molecular EvolutionHot TemperatureMicrofluidicsNADTemperatureEnzyme StabilityAldehyde DehydrogenaseButanolsisobutyl alcoholNADabsorbance‐activated droplet sortingaldehyde dehydrogenasedirected evolutionisobutanolthermostability

Identifiers

PMID40539308
PMCPMC12548936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.