Evidence map›Paper›PMID 40539259›Full record

Trial reportJournal of the International Society of Sports Nutrition2025

Neither pre-sleep nor post-exercise protein consumption influences resistance exercise training adaptations in older adults.

Alex O Klemp, Michael J Ormsbee, Mingchia Yeh, Chester M Sokolowski, Do-Houn Kim, Lynn B Panton, Jeong-Su Kim

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05922475 (Neither Pre-sleep Nor Post-exercise Protein Consumption Influences Resistance Exercise Training Adaptations in Older Adults), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05922475 nacompletednot on this map

Neither Pre-sleep Nor Post-exercise Protein Consumption Influences Resistance Exercise Training Adaptations in Older Adults

TypeinterventionalSponsorFlorida State UniversityRan2017 to 2019Enrolled32ConditionsAgingArmsProtein, Placebo
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alex O KlempFlorida State University, Department of Nutrition and Integrative Physiology, Tallahassee, FL, USA.ORCID 0000-0002-1050-5163
Michael J OrmsbeeFlorida State University, Department of Nutrition and Integrative Physiology, Tallahassee, FL, USA.
Mingchia YehSlippery Rock University, Department of Exercise Science, Slippery Rock, PA, USA.
Chester M SokolowskiFlorida State University, Department of Nutrition and Integrative Physiology, Tallahassee, FL, USA.
Do-Houn KimGonzaga University, Department of Kinesiology and Sport Management, Spokane, WA, USA.
Lynn B PantonFlorida State University, Department of Nutrition and Integrative Physiology, Tallahassee, FL, USA.
Jeong-Su KimFlorida State University, Department of Nutrition and Integrative Physiology, Tallahassee, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLimited data exists that compare pre-sleep versus post-exercise protein intake during resistance exercise training (RET) in older adults. This study examined whether 40 g of protein consumed post-exercise (PRP) or pre-sleep (PSP) enhances muscle thickness (MT) and strength compared to RET alone (RETO) in older men.

methodsThirty untrained older men (65.7 ± 4.0 yrs) completed 12 weeks of supervised RET (2×/week) and were randomized to PRP (

resultsVL (0 to 12 weeks: + 0.16 cm, 95% C.I. [0.06, 0.25]), RF (0 to 12 weeks: + 0.13 cm, 95% C.I. [0.03, 0.23]), and VI MT (0 to 12 weeks: + 0.18 cm, 95% C.I. [0.05, 0.31]) and chest press (0 to 12 weeks: + 10.9 kg, 95% C.I. [5.50, 16.3]) and leg press (0 to 12 weeks: + 28.3 kg, 95% C.I. [19.63, 37.1]) 1-RM increased (

conclusionConsuming 40 g of protein post-exercise or pre-sleep did not enhance RET-induced improvements in muscle thickness or strength in older adults with adequate baseline protein intake (≥1.0 g/kg/day). RET alone elicited significant gains, emphasizing that adherence to training and meeting daily protein requirements are more critical than timing strategies for untrained older adults. ClinicalTrials.gov identifier: NCT05922475, 06/23/2023, retrospectively registered.

Indexed as

Adaptation, PhysiologicalDietary ProteinsResistance TrainingSleepAgedHumansMaleMiddle AgedMuscle, SkeletalMuscle StrengthQuadriceps MuscleDietary Proteinshypertrophymuscle strengthmuscle thicknessolder adultsproteinResistance exercise

Identifiers

PMID40539259
PMCPMC12897527

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.