Evidence map›Paper›PMID 40539172›Full record

ArticleCureus2025

The Effectiveness of Combined Mirror Therapy and Contralateral Controlled Functional Electrical Stimulation Therapy in a Stroke Patient With Upper Limb Motor Paralysis: A Case Report.

Keiichiro Aoki, Kengo Uchibori, Takayuki Watabe, Akira Yoshikawa, Nobiyuki Kawate

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keiichiro AokiDivision of Occupational Therapy, Department of Rehabilitation, School of Nursing and Rehabilitation Sciences, Showa Medical University, Yokohama, JPN.
Kengo UchiboriRehabilitation Center, Showa Medical University Fujigaoka Rehabilitation Hospital, Yokohama, JPN.
Takayuki WatabeRehabilitation Center, Showa Medical University Fujigaoka Rehabilitation Hospital, Yokohama, JPN.
Akira YoshikawaDivision of Health Science Education, School of Nursing and Rehabilitation Sciences, Showa Medical University, Yokohama, JPN.
Nobiyuki KawateDepartment of Rehabilitation Medicine, Graduate School of Medicine, Showa Medical University, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe upper limb motor paralysis following a stroke significantly limits patients' daily function and quality of life. While traditional therapies like constraint-induced therapy, muscle strengthening, and exercise are commonly used, they often lack effectiveness for severe cases due to their reliance on voluntary movement. In contrast, mirror therapy and contralaterally controlled functional electrical stimulation (CCFES) have shown potential by directly engaging neural pathways to promote recovery. This case report describes combining two methods to create a more effective approach for enhancing motor recovery in patients with severe upper limb deficits. A 59-year-old Japanese male presented with left hemiplegia following a right subcortical hemorrhage. Following craniotomy and cranioplasty, he was transferred to our facility for rehabilitation. Upon initiation of occupational therapy, comprehensive assessments revealed profound motor impairments in the left upper extremity, with a Fugl-Meyer Assessment-Upper Extremity (FMA-UE) score of 17/66 at the start of therapy and initial Motor Activity Log (MAL) scores of amount of use (AOU) 1.5 and quality of movement (QOM) 1.0 at week four. A combined regimen of mirror therapy and CCFES was administered over 16 weeks. During this time, the patient exhibited substantial improvements in motor function, with the FMA-UE score increasing to 52/66 and the MAL scores improving to AOU 3.6 and QOM 3.9 by week 16. This study suggests that a rehabilitation strategy combining mirror therapy with CCFES can effectively enhance motor recovery in patients with severe upper limb motor paralysis. However, these findings should be interpreted with caution as they are based on a preliminary single-patient case study. Further research with larger sample sizes is needed to confirm the efficacy of this combined approach and assess its long-term benefits.

Indexed as

case reportelectrical stimulationmirror therapystroke rehabilitationupper limb paralysis

Identifiers

PMID40539172
PMCPMC12177207

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