Evidence map›Paper›PMID 40539152›Full record

ArticleCureus2025

Social Determinants and Prevention Strategies in the HIV Epidemic: The National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) Database Analysis.

Edediong Ekarika, Charity Iheagwara, Adaora T Amadi, Patra C Ezeamii, Michael O Oluwalana, Linda C Ihuoma, Ogechukwu H Nnabude, Nenrot S Gopep, Okelue E Okobi, Nnenna B Emejuru

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Edediong EkarikaPublic Health, Emory University, Rollins School of Public Health, Atlanta, USA.
Charity IheagwaraInfectious Diseases, Saint Michael's Medical Center, Newark, USA.
Adaora T AmadiFamily Medicine, Enugu State University, College of Medicine, Enugu, NGA.
Patra C EzeamiiEpidemiology and Public Health, Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, USA.
Michael O OluwalanaFaculty of Medicine, Memorial University of Newfoundland, St. John's, CAN.
Linda C IhuomaInternal Medicine, University of Port Harcourt Teaching Hospital, Choba, NGA.
Ogechukwu H NnabudeDermatology, Psychiatry, Cardiology, Internal Medicine, Family Medicine, Windsor University School of Medicine, St. Kitts, KNA.
Nenrot S GopepCommunity Medicine, Federal Medical Center, Keffi, NGA.
Okelue E OkobiFamily Medicine, IMG Research Academy & Consulting, Miami, USA.
Nnenna B EmejuruPsychiatry and Behavioral Sciences, College of Medicine, Imo State University, Orlu, NGA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe human immunodeficiency virus (HIV) epidemic remains a significant public health challenge, with social determinants and prevention strategies playing a crucial role in disease outcomes. While advancements in treatment and prevention have led to improvements in viral suppression and healthcare access, disparities in healthcare remain, particularly among vulnerable populations.

aimThis study analyzes HIV epidemiological trends, healthcare access, and social determinants influencing the HIV epidemic in the United States from 2018 to 2022, using data from the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) database.

methodA retrospective analysis of national surveillance data was conducted to assess trends in HIV-related mortality, viral suppression, incidence, prevalence, and healthcare access. Key indicators such as knowledge of HIV status, PrEP coverage, linkage to care, HIV stigma, and unstable housing were evaluated. Data were analyzed for temporal trends, with a focus on the impact of the COVID-19 pandemic on HIV outcomes.

resultsThe findings indicate a reduction in new HIV infections and an increase in HIV prevalence, suggesting improvements in diagnosis and treatment. Although AIDS-related and HIV-related deaths spiked during the COVID-19 pandemic, viral suppression rates steadily improved. Healthcare access remained stable, with increased PrEP coverage and linkage to care. However, persistent barriers such as HIV stigma and unstable housing continued to affect health outcomes.

conclusionThe study highlights significant progress in HIV prevention and care but underscores the need for targeted interventions addressing social determinants. Continued investment in equitable healthcare access, stigma reduction, and housing stability is essential for sustaining control of the HIV epidemic.

Indexed as

hivhiv diseaseshiv epidemichiv preventionsocial determinant

Identifiers

PMID40539152
PMCPMC12177844

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.