ArticleClinical Medicine Insights. Oncology2025
Antibiotic Usage During Surgery may be Correlated With Survival in Radically Resected Non-Small-Cell Lung Cancer Patients.
Article in Clinical Medicine Insights. Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Background: Accumulating evidence suggests that the use of antibiotics (ATBs) is harmful to the survival of patients with non-small-cell lung cancer (NSCLC). However, the association between the prophylactic use of these agents during surgery and patient survival has been less well studied. Methods: Data concerning the use of ATBs, including the cumulative defined daily dose (cDDD) and type, in stage I to III NSCLC patients were collected. The patients were subsequently divided into low or high-cDDD subgroups and ⩽2 or ⩾3 ATB-type subgroups. Differences in clinical variables, overall survival (OS), and disease-free survival (DFS) among these groups were assessed. Furthermore, differences in survival among specific ATB types ( Results: A total of 324 patients were included. Low cDDD was more common in patients with advanced T stages, whereas ⩽2 types of ATBs were common in female patients and those with adenocarcinoma, N Conclusions: This study, for the first time, explored the prognostic value of ATB use during surgery in NSCLC patients and revealed that multiple types of ATBs may be associated with OS in patients with stage I to III disease. Notably, patients treated with
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