Evidence map›Paper›PMID 40538513›Full record

SynthesisWorld journal of gastroenterology2025

Artificial intelligence for reducing missed detection of adenomas and polyps in colonoscopy: A systematic review and meta-analysis.

Sheng-Yu Wang, Jia-Cheng Gao, Shuo-Dong Wu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sheng-Yu WangThe Second Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.
Jia-Cheng GaoDepartment of Orthopedic Surgery, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Shuo-Dong WuDepartment of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China. 13909824526@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer has a high incidence and mortality rate, and the effectiveness of routine colonoscopy largely depends on the endoscopist's expertise. In recent years, computer-aided detection (CADe) systems have been increasingly integrated into colonoscopy to improve detection accuracy. However, while most studies have focused on adenoma detection rate (ADR) as the primary outcome, the more sensitive adenoma miss rate (AMR) has been less frequently analyzed.

aimTo evaluate the effectiveness of CADe in colonoscopy and assess the advantages of AMR over ADR.

methodsA comprehensive literature search was conducted in PubMed, Embase, and the Cochrane Central Register of Controlled Trials using predefined search strategies to identify relevant studies published up to August 2, 2024. Statistical analyses were performed to compare outcomes between groups, and potential publication bias was assessed using funnel plots. The quality of the included studies was evaluated using the Cochrane Risk of Bias tool and the Grading of Recommendations, Assessment, Development, and Evaluation approach.

resultsFive studies comprising 1624 patients met the inclusion criteria. AMR was significantly lower in the CADe-assisted group than in the routine colonoscopy group (147/927, 15.9%

conclusionCADe can significantly reduce AMR and PMR while improving ADR during initial detection, demonstrating its potential to enhance colonoscopy performance. These findings highlight the value of CADe in improving the detection of colorectal neoplasms, particularly small and histologically distinct adenomas.

Indexed as

AdenomaArtificial IntelligenceColonic PolypsColonoscopyColorectal NeoplasmsMissed DiagnosisEarly Detection of CancerHumansArtificial intelligenceColonoscopyComputer-aided detectionNeoplasmsPrevention and control

Identifiers

PMID40538513
PMCPMC12175867

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.